Function of mysterious RNAs may often lie in their genes
Scientists from Penn Medicine and other institutions unlock a mystery about 'long non-coding RNAs'. A new genetic clue discovered by a team co-led by a researcher at the Perelman School of Medicine at the University of Pennsylvania is shedding light on the functions of the mysterious "long non-coding RNAs" (lncRNAs). These molecules are transcribed from genes and are often abundant in cells, yet they do not code for proteins. Their functions have been almost entirely unknown--and in recent years have attracted much research and debate.
Molecular & Cell Biology
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Human kidney progenitors isolated, offering new clues to cell renewal
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Scientists uncover the way a common cell enzyme alerts the body to invading bacteria
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Calcium channel blockers caught in the act at atomic level
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Genetic regulation of the thymus function identified
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Nobel laureate, new technologies show how cancer cells protect chromosomes from decay
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A molecular alarm clock awakens resting ovules
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Neuron unites 2 theoretical models on motion detection
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Scientific serendipity yields new neuron type in mouse retina
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Researchers find how proteins control gene expression by binding both DNA and RNA
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TSRI researchers find 'lead actors' in immune cell development
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UMD researchers discover a way that animals keep their cells identical
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Cell death: How a protein drives immune cells to suicide
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Viruses revealed to be a major driver of human evolution
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Open chromatin profiling key to identifying leukemia cells of origin
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The importance of keeping silent...in breast cancer cells