Toplam 83 içerik listeleniyor
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Gene therapy treats all muscles in the body in muscular dystrophy dogs
Muscular dystrophy, which affects approximately 250,000 people in the U.S., occurs when damaged muscle tissue is replaced with fibrous, fatty or bony tissue and loses function. For years, scientists have searched for a way to successfully treat the most common form of the disease, Duchenne Muscular Dystrophy (DMD), which primarily affects boys. Now, a team of University of Missouri researchers have successfully treated dogs with DMD and say that human clinical trials are being planned in the...
https://www.biyologlar.com/gene-therapy-treats-all-muscles-in-the-body-in-muscular-dystrophy-dogs-haber-8760 -
Cell stress inflames the gut
Over 3.5 million people in Europe and the US suffer from Crohn's disease or ulcerative colitis – the two most common forms of IBD. Chronic bowel inflammation is caused by an overreaction of the immune system to the bacteria which naturally occur in the gut. "This overreaction can come about if, for example, the anti-stress mechanism in the cells of the intestinal mucosa does not function correctly," explains Prof. Dirk Haller of the TUM Chair of Nutrition and Immunology. What Prof. Haller is...
https://www.biyologlar.com/cell-stress-inflames-the-gut -
Stem cells + nanofibers = Promising nerve research
Every week in his clinic at the University of Michigan, neurologist Joseph Corey, M.D., Ph.D., treats patients whose nerves are dying or shrinking due to disease or injury.
https://www.biyologlar.com/stem-cells-nanofibers-promising-nerve-research -
Improving the delivery of chemotherapy with graphene
A new study published in IOP Publishing's journal 2D Materials has proposed using graphene as an alternative coating for catheters to improve the delivery of chemotherapy drugs. The research suggests that placing graphene - an extremely thin sheet of carbon atoms - on the internal surfaces of intravenous catheters commonly used to deliver chemotherapy drugs into a patient's body will improve the efficacy of treatments, and reduce the potential of the catheters breaking. The study indicates...
https://www.biyologlar.com/improving-the-delivery-of-chemotherapy-with-graphene -
CRISPR/ Cas9 Gen Düzenleme Düşünülenden Daha Fazla Genetik Hasara Neden Olabilir
CRISPR / Cas9 gen düzenlemesinde genom hasarı düşünülenden daha yüksek olabilir. Potansiyel gen terapilerinde CRISPR / Cas9 kullanımı için dikkat edilmesi gerekir.
https://www.biyologlar.com/crispr-cas9-gen-duzenleme-daha-once-dusunulenden-daha-fazla-genetik-hasar-neden-olabilir -
CRISPR/ Cas9 Gen Düzenleme Düşünülenden Daha Fazla Genetik Hasara Neden Olabilir
CRISPR / Cas9 gen düzenlemesinde genom hasarı düşünülenden daha yüksek olabilir. Potansiyel gen terapilerinde CRISPR / Cas9 kullanımı için dikkat edilmesi gerekir.
https://www.biyologlar.com/crispr-cas9-gen-duzenleme-daha-once-dusunulenden-daha-fazla-genetik-hasar-neden-olabilir -
Satellites show 'total' California water storage at near-decade low
Updates to satellite data show that California's Sacramento and San Joaquin River basins are at near decade-low water storage levels. These and other findings on the State's dwindling water resources were documented in an advisory report released today from the UC Center for Hydrologic Modeling (UCCHM) at the University of California, Irvine. Responding to Governor Jerry Brown's recent declaration of a drought emergency in California, a team of UCCHM researchers has updated its research on the...
https://www.biyologlar.com/satellites-show-total-california-water-storage-at-near-decade-low -
Stem-cell approach shows promise for Duchenne muscular dystrophy
Researchers have shown that transplanting stem cells derived from normal mouse blood vessels into the hearts of mice that model the pathology associated with Duchenne muscular dystrophy (DMD) prevents the decrease in heart function associated with DMD. Their findings appear in the journal Stem Cells Translational Medicine. Duchenne muscular dystrophy is a genetic disorder caused by a mutation in the gene for dystrophin, a protein that anchors muscle cells in place when they contract. Without...
https://www.biyologlar.com/stem-cell-approach-shows-promise-for-duchenne-muscular-dystrophy -
Stem cell breakthrough could set up future transplant therapies
A new method for creating stem cells for the human liver and pancreas, which could enable both cell types to be grown in sufficient quantities for clinical use, has been developed by scientists. Using the technique, researchers have for the first time been able to grow a pure, self-renewing population of stem cells specific to the human foregut, the upper section of the human digestive system. These so-called "Foregut stem cells" could then be developed further to produce liver or pancreatic...
https://www.biyologlar.com/stem-cell-breakthrough-could-set-up-future-transplant-therapies -
Ascaris lumbricoides
Ascaris lumbricoides is otherwise known as the large intestinal roundworm of humans. It looks a lot like a large earthworm, but the two are not related. The earthworm is an annelid; it lives in the soil, feeding on organic debris. A. lumbricoides is a parasitic nematode, or roundworm; adults are found only in the intestines of humans, feeding on intestinal contents as they flow past. If you were to compare the two very carefully, you would note that the earthworm has little tufts of bristles...
https://www.biyologlar.com/ascaris-lumbricoides -
Damaged DNA may stall patrolling molecule to initiate repair
Sites where DNA is damaged may cause a molecule that slides along the DNA strand to scan for damage to slow on its patrol, delaying it long enough to recognize and initiate repair. The finding suggests that the delay itself may be the key that allows the protein molecule to find its target, according to researchers at the University of Illinois at Chicago. Usually, the repair protein zips along quickly, says Anjum Ansari, UIC professor of physics and co-principal investigator on the study,...
https://www.biyologlar.com/damaged-dna-may-stall-patrolling-molecule-to-initiate-repair -
Stem cells might heal damaged lungs
Collectively, such diseases of the airways as emphysema, bronchitis, asthma and cystic fibrosis are the second leading cause of death worldwide.
https://www.biyologlar.com/stem-cells-might-heal-damaged-lungs -
Great Barrier Reef marine reserves combat coral disease
A new and significant role for marine reserves on the Great Barrier Reef has been revealed, with researchers finding the reserves reduce the prevalence of coral diseases. It's been known for some time that marine reserves are important for maintaining and enhancing fish stocks, but this is the first time marine reserves have been shown to enhance coral health on the Great Barrier Reef. Researchers from the ARC Centre of Excellence for Coral Reef Studies at James Cook University found that...
https://www.biyologlar.com/great-barrier-reef-marine-reserves-combat-coral-disease -
Proteomics identifies DNA repair toolbox
During each cell division, more than 3.3 billion base pairs of genomic DNA have to be duplicated and segregated accurately to daughter cells. But what happens when the DNA template is damaged in such a way that the replication machinery gets stuck?
https://www.biyologlar.com/proteomics-identifies-dna-repair-toolbox -
Tough times for the tree of life on coral reefs
Marine scientists are calling for a re-think of how marine protected areas (MPAs) are planned and coordinated, following a global assessment of the conservation of tropical corals and fishes. Researchers from the Australian Research Council Centre of Excellence for Coral Reef Studies (Coral CoE), at James Cook University in Townsville, analysed the extent to which the evolutionary histories of corals and fishes are protected, rather than looking at individual species. "Our interest was in...
https://www.biyologlar.com/tough-times-for-the-tree-of-life-on-coral-reefs -
Nerve cells use each other as maps
When nerve cells form in an embryo they do not start off in the right place but have to be guided to their final position by navigating a kind of molecular and cellular "map" in order to function properly. In a recent research study published in Nature Communications neurobiologist Sara Wilson, Umeå University, found that during embryonic development different parts of the nerve cell are important for guiding other nerve cells into their physical positions. "We found nerve cells do this in...
https://www.biyologlar.com/nerve-cells-use-each-other-as-maps -
Researchers build molecule that could significantly reduce brain damage in stroke victims
Research teams separated by 14 hours and 9,000 miles have collaborated to advance prospective treatment for the world's second-leading cause of death. University of Nebraska-Lincoln chemists partnered with medical researchers from the National University of Singapore to develop a molecule that can inhibit an enzyme linked with the onset of stroke. Most strokes occur when a disruption of blood flow prevents oxygen and glucose from reaching brain tissue, ultimately killing neurons and other...
https://www.biyologlar.com/researchers-build-molecule-that-could-significantly-reduce-brain-damage-in-stroke-victims -
Griffith uses 3-D tissue engineering to revolutionize dental disease
The discomfort and stigma of loose or missing teeth could be a thing of the past as Griffith University researchers pioneer the use of 3D bioprinting to replace missing teeth and bone. The three-year study, which has been granted a National Health and Medical Research Council Grant of $650,000, is being undertaken by periodontist Professor Saso Ivanovski from Griffith's Menzies Health Institute Queensland. As part of an Australian first, Professor Ivanovski and his team are using the latest...
https://www.biyologlar.com/griffith-uses-3-d-tissue-engineering-to-revolutionize-dental-disease -
These gigantic whales have nerves like bungee cords
Nerves aren't known for being stretchy. In fact, "nerve stretch injury" is a common form of trauma in humans. But researchers reporting in
https://www.biyologlar.com/these-gigantic-whales-have-nerves-like-bungee-cords -
Mantis shrimp inspires next generation of ultra-strong materials
This is the herringbone structure of the outer layer (impact region) of the mantis shrimp dactyl club.
https://www.biyologlar.com/mantis-shrimp-inspires-next-generation-of-ultra-strong-materials -
Mantis shrimp inspires next generation of ultra-strong materials
This is the herringbone structure of the outer layer (impact region) of the mantis shrimp dactyl club.
https://www.biyologlar.com/mantis-shrimp-inspires-next-generation-of-ultra-strong-materials -
Stem cell transplant from young to old can heal stomach ulcers
Bethesda, MD (June 16, 2016) -- Basic and translational research paves the way for breakthroughs that can ultimately change patient care. Three new studies from Cellular and Molecular Gastroenterology and Hepatology (CMGH) -- AGA's basic and translational open-access journal -- provide a glimpse into future treatment strategies for stomach ulcers, inflammatory bowel disease and alcoholic liver disease. Please find summaries below. To speak with the journal authors, please email...
https://www.biyologlar.com/stem-cell-transplant-from-young-to-old-can-heal-stomach-ulcers -
DNA damage by ultrashort pulses of intense laser light
DNA damage caused by very low-energy electrons and OH-radicals formed upon irradiation of water by ultrashort pulses of very intense laser light.
https://www.biyologlar.com/dna-damage-by-ultrashort-pulses-of-intense-laser-light -
DNA damage by ultrashort pulses of intense laser light
DNA damage caused by very low-energy electrons and OH-radicals formed upon irradiation of water by ultrashort pulses of very intense laser light.
https://www.biyologlar.com/dna-damage-by-ultrashort-pulses-of-intense-laser-light -
Gene controls regeneration of injured muscle by adult stem cells
A key gene enables the repair of injured muscle throughout life. This is the finding of a study in mice led by researchers at NYU Langone Medical Center and the University of Colorado at Boulder, and published online July 21 in Cell Reports.
https://www.biyologlar.com/gene-controls-regeneration-of-injured-muscle-by-adult-stem-cells -
Disease that causes blindness in children tied to new gene
Northwestern Medicine and University of Wisconsin-Madison (UW) scientists have identified a gene that causes severe glaucoma in children.
https://www.biyologlar.com/disease-that-causes-blindness-in-children-tied-to-new-gene -
In some genetic cases of microcephaly, stem cells fail to launch
In a very severe, genetic form of microcephaly, stem cells in the brain fail to divide, according to a new Columbia University Medical Center study that may provide important clues to understanding how the Zika virus affects the developing brain.
https://www.biyologlar.com/in-some-genetic-cases-of-microcephaly-stem-cells-fail-to-launch -
Scientists blueprint tiny cellular 'nanomachine'
Scientists have drawn up molecular blueprints of a tiny cellular 'nanomachine', whose evolution is an extraordinary feat of nature, by using one of the brightest X-ray sources on Earth. The scientists produced the structural map of this nanomachine - diacylglycerol kinase - by using a "hit and run" crystallography technique. In doing so, they have been able to understand how the tiny enzyme performs critical cellular duties - answering questions that have been on the table for over 50 years...
https://www.biyologlar.com/scientists-blueprint-tiny-cellular-nanomachine -
DNA research offers clues on cell mutation
A team of researchers from Colorado State University has been studying DNA damage in living cells to learn more about how genetic abnormalities arise. It has long been known that DNA molecules in every cell get constantly damaged by things from the outside environment, like sunlight, cigarette smoke and radiation. However, more recently researchers have discovered that sources from within the cell itself can sometimes be even more damaging. DNA, or deoxyribonucleic acid, is found in the...
https://www.biyologlar.com/dna-research-offers-clues-on-cell-mutation -
DNA research offers clues on cell mutation
A team of researchers from Colorado State University has been studying DNA damage in living cells to learn more about how genetic abnormalities arise. It has long been known that DNA molecules in every cell get constantly damaged by things from the outside environment, like sunlight, cigarette smoke and radiation. However, more recently researchers have discovered that sources from within the cell itself can sometimes be even more damaging. DNA, or deoxyribonucleic acid, is found in the...
https://www.biyologlar.com/dna-research-offers-clues-on-cell-mutation -
Scientists discover protein's starring role in genome stability, and possibly cancer prevention
If you have a soft spot for unsung heroes, you'll love a DNA repair protein called XPG. Scientists from the U.S. Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) discovered that XPG plays a previously unknown and critical role helping to maintain genome stability in human cells. Their findings also raise the possibility that the protein helps prevent breast, ovarian, and other cancers associated with defective BRCA genes. The research, which is published online Jan....
https://www.biyologlar.com/scientists-discover-proteins-starring-role-in-genome-stability-and-possibly-cancer-prevention -
New DNA research reveals genetic heritage of elusive vaquita
A new method of teasing information from scarce and highly degraded genetic samples is helping NOAA Fisheries and Mexican scientists unravel the genetic heritage of the enigmatic vaquita, the most endangered marine mammal on Earth. Genetic studies are important to the international effort to conserve the vaquita because the DNA that holds their genetic code can unlock the secrets of how they came to be. For instance, it can reveal the story of how - and how long ago - the animals evolved into...
https://www.biyologlar.com/new-dna-research-reveals-genetic-heritage-of-elusive-vaquita -
New DNA research reveals genetic heritage of elusive vaquita
A new method of teasing information from scarce and highly degraded genetic samples is helping NOAA Fisheries and Mexican scientists unravel the genetic heritage of the enigmatic vaquita, the most endangered marine mammal on Earth. Genetic studies are important to the international effort to conserve the vaquita because the DNA that holds their genetic code can unlock the secrets of how they came to be. For instance, it can reveal the story of how - and how long ago - the animals evolved into...
https://www.biyologlar.com/new-dna-research-reveals-genetic-heritage-of-elusive-vaquita -
Searching for an ancient syphilis DNA in newborns
The ancient bones of newborns are very useful to recover the ancient DNA of the bacteria causing syphilis, the Treponema pallidum pallidum. This is the conclusion reached by a study led by Universitat Autònoma de Barcelona (UAB), which was able to obtain the genetic material from the bacteria in more than one individual, in what is considered to be the oldest case known to date. Several previous intents had only achieved to yield this material in one occasion and from only one...
https://www.biyologlar.com/searching-for-an-ancient-syphilis-dna-in-newborns -
Cells check DNA segregation at the end of their division
The cells in our bodies are constantly dividing. From embryonic development to adult life, cell division is necessary for tissue growth and renewal.
https://www.biyologlar.com/cells-check-dna-segregation-at-the-end-of-their-division -
May repairs full of mistakes develop into cancer?
These are DNA double-strand breaks, introduced by ionizing radiation or other mechanisms, are repaired rapidly and precisely in normal cells (right pathway). In contrast, compromised Tel1 activation with inefficient end...
https://www.biyologlar.com/may-repairs-full-of-mistakes-develop-into-cancer -
May repairs full of mistakes develop into cancer?
These are DNA double-strand breaks, introduced by ionizing radiation or other mechanisms, are repaired rapidly and precisely in normal cells (right pathway). In contrast, compromised Tel1 activation with inefficient end...
https://www.biyologlar.com/may-repairs-full-of-mistakes-develop-into-cancer -
Bacterial DNA may integrate into human genome more readily in tumor tissue
Bacterial DNA may integrate into the human genome more readily in tumors than in normal human tissue, scientists have found. The researchers, affiliated with the University of Maryland School of Medicine's Institute for Genome Sciences, analyzed genomic sequencing data available from the Human Genome Project, the 1,000 Genomes Project and The Cancer Genome Atlas. They considered the phenomenon of lateral gene transfer (LGT), the transmission of genetic material between organisms in a manner...
https://www.biyologlar.com/bacterial-dna-may-integrate-into-human-genome-more-readily-in-tumor-tissue -
An unexpected origin for calming immune cells in the gut
Biologically speaking, we carry the outside world within us. The food we ingest each day and the trillions of microbes that inhabit our guts pose a constant risk of infection--and all that separates us from these foreign entities is a delicate boundary made of a single layer of cells. The immune cells that swarm about this threshold must exercise a precise balancing act. They must be vigilant, yet also tolerant of harmless substances so that they don't cause harmful overreactions. New research...
https://www.biyologlar.com/an-unexpected-origin-for-calming-immune-cells-in-the-gut -
DNA breaks in nerve cells' ancestors cluster in specific genes
The genome of developing brain cells harbors 27 clusters or hotspots where its DNA is much more likely to break in some places than others, researchers from the Program in Cellular and Molecular Medicine (PCMM) at Boston Children's Hospital, Harvard Medical School, and the Howard Hughes Medical Institute report in the journal Cell. Those hotspots appear in genes associated with brain tumors and a number of neurodevelopmental and neuropsychiatric conditions, raising new questions about these...
https://www.biyologlar.com/dna-breaks-in-nerve-cells-ancestors-cluster-in-specific-genes -
DNA breaks in nerve cells' ancestors cluster in specific genes
The genome of developing brain cells harbors 27 clusters or hotspots where its DNA is much more likely to break in some places than others, researchers from the Program in Cellular and Molecular Medicine (PCMM) at Boston Children's Hospital, Harvard Medical School, and the Howard Hughes Medical Institute report in the journal Cell. Those hotspots appear in genes associated with brain tumors and a number of neurodevelopmental and neuropsychiatric conditions, raising new questions about these...
https://www.biyologlar.com/dna-breaks-in-nerve-cells-ancestors-cluster-in-specific-genes -
Researchers discover two new groups of viruses
Researchers at the University of Bonn and the German Center for Infection Research (DZIF) have discovered two new groups of viruses within the Bunyavirus family in the tropical forest of Ivory Coast. Previously only five groups responsible for serious illnesses in humans and animals were known. Most are spread through blood-feeding insects. Based on the discovered viruses researchers conclude that the ancester to all bunyaviruses must have existed in arthropods such as insects. The results are...
https://www.biyologlar.com/researchers-discover-two-new-groups-of-viruses -
Mouse models show how Zika infects a fetus during pregnancy
Researchers at Washington University in St. Louis (WashU) have established the first models of Zika virus transmission from a pregnant mouse to her fetus.
https://www.biyologlar.com/mouse-models-show-how-zika-infects-a-fetus-during-pregnancy -
Mouse models show how Zika infects a fetus during pregnancy
Researchers at Washington University in St. Louis (WashU) have established the first models of Zika virus transmission from a pregnant mouse to her fetus.
https://www.biyologlar.com/mouse-models-show-how-zika-infects-a-fetus-during-pregnancy -
Protein structure paves the way for new broad spectrum antifungals
This ribbon diagram shows two views of the structure of the enzyme Tps2 as it removes a phosphate from a sugar molecule (yellow, orange and red).
https://www.biyologlar.com/protein-structure-paves-the-way-for-new-broad-spectrum-antifungals -
Discovery of new hepatitis C virus mechanism
SPP inhibition reduces production of infectious HCV particles and pathogenesis,
https://www.biyologlar.com/discovery-of-new-hepatitis-c-virus-mechanism -
Discovery of new hepatitis C virus mechanism
SPP inhibition reduces production of infectious HCV particles and pathogenesis,
https://www.biyologlar.com/discovery-of-new-hepatitis-c-virus-mechanism -
Forest Elephants – The New Yorker (2015)
African forest elephants have been featured in quite a few documentaries including the tropical rainforests episode of the Planet Earth series. Here in this short documentary we listen to Andrea Turkalo’s wonderful lecture on behavior of these charismatic megafaunal animals. She has been observing the elephants in Dzanga Research Camp at the Dzanga-Sangha National Park in Central African Republic for more than two decades. Andrea Turkalo is Associate Conservation Scientist at the Wildlife...
https://www.biyologlar.com/forest-elephants-the-new-yorker-2015 -
XXV International Congress of Entomology
ESA is honored to host ICE 2016, the XXV International Congress of Entomology, under the theme Entomology without Borders. The event is expected to bring together the largest delegation of scientists and experts in the history of the discipline, who will meet in exciting, easily-accessible, and affordable Orlando, Florida, USA. Make important connections with entomologists and scientists from around the world. Present to this global audience and compete in global competitions. Participate in...
https://www.biyologlar.com/xxv-international-congress-of-entomology -
Galaktozeminin Genetiği
Galaktozemiden etkilenmeyen (ne taşıyıcı ne de galaktozemik) biri, GALT enzim (galaktozu vücut için kullanılabilir hale getirmek için gerekli enzim) üretimi için iki normal gen devralır. Bu kişinin genotipi N/N' dir ve enzim aktivitesi normal olur. Klasik galaktozemi taşıyıcısı biri bir ebeveynden normal, diğerinden de klasik galaktozemiye yol açan hatayı kapsayan bir gen alır. Bu kişinin genotipi G/N' dir ve enzim aktivitesi normalden az ama tıbbi komplikasyonlara yol...
https://www.biyologlar.com/galaktozeminin-genetigi