Toplam 163 içerik listeleniyor
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Gene therapy: A promising candidate for cystic fibrosis treatment
An improved gene therapy treatment can cure mice with cystic fibrosis (CF). Cell cultures from CF patients, too, respond well to the treatment. Those are the encouraging results of a study presented by the Laboratory for Molecular Virology and Gene Therapy at KU Leuven, Belgium.
https://www.biyologlar.com/gene-therapy-a-promising-candidate-for-cystic-fibrosis-treatment-haber-8759 -
Telomerlerin Yaşlanma Ve Kanser İlişkisindeki Rolü
Telomerlerin yaşlanma ve kanser ilişkisindeki rolü oldukça önemlidir. Kanser tedavisinde ve teşhisinde geleneksel yöntemlerin yanı sıra telomeraz aktivitesinin ölçümü özgün bir belirteç olarak kullanılabilir.
https://www.biyologlar.com/telomerlerin-yaslanma-ve-kanser-iliskisindeki-rolu -
Telomerlerin Yaşlanma Ve Kanser İlişkisindeki Rolü
Telomerlerin yaşlanma ve kanser ilişkisindeki rolü oldukça önemlidir. Kanser tedavisinde ve teşhisinde geleneksel yöntemlerin yanı sıra telomeraz aktivitesinin ölçümü özgün bir belirteç olarak kullanılabilir.
https://www.biyologlar.com/telomerlerin-yaslanma-ve-kanser-iliskisindeki-rolu -
Improving the delivery of chemotherapy with graphene
A new study published in IOP Publishing's journal 2D Materials has proposed using graphene as an alternative coating for catheters to improve the delivery of chemotherapy drugs. The research suggests that placing graphene - an extremely thin sheet of carbon atoms - on the internal surfaces of intravenous catheters commonly used to deliver chemotherapy drugs into a patient's body will improve the efficacy of treatments, and reduce the potential of the catheters breaking. The study indicates...
https://www.biyologlar.com/improving-the-delivery-of-chemotherapy-with-graphene -
New discovery in living cell signaling
A breakthrough discovery into how living cells process and respond to chemical information could help advance the development of treatments for a large number of cancers and other cellular disorders that have been resistant to therapy. An international collaboration of researchers, led by scientists with the U.S. Department of Energy (DOE)'s Lawrence Berkeley National Laboratory (Berkeley Lab) and the University of California (UC) Berkeley, have unlocked the secret behind the activation of the...
https://www.biyologlar.com/new-discovery-in-living-cell-signaling -
Stem-cell approach shows promise for Duchenne muscular dystrophy
Researchers have shown that transplanting stem cells derived from normal mouse blood vessels into the hearts of mice that model the pathology associated with Duchenne muscular dystrophy (DMD) prevents the decrease in heart function associated with DMD. Their findings appear in the journal Stem Cells Translational Medicine. Duchenne muscular dystrophy is a genetic disorder caused by a mutation in the gene for dystrophin, a protein that anchors muscle cells in place when they contract. Without...
https://www.biyologlar.com/stem-cell-approach-shows-promise-for-duchenne-muscular-dystrophy -
Kanser Tedavisine Bakteriler ve Nano Robotlar
Kana enjekte edilen ilaçların hastalıklı hücrelere adrese teslim ve nokta atışı ulaştığı zamanların eşiğindeyiz. Bizleri gereksiz bıçakaltı işlemlerden ve ilaçların yan etkilerinden koruyacak, bakteri ve nano robotların insanların iyiliği için işbirliği yaptıkları tıbbi yöntemleri inceleyeceğiz.Askerleri küçültüp mikro boyutlara getirebilecek teknolojinin sırrına sahip bilim adamı Jan Benes, CIA ajanlarının yardımıyla SSCB’den kaçar. Ancak bu esnada...
https://www.biyologlar.com/kanser-tedavisine-bakteriler-ve-nano-robotlar -
Simple technology makes CRISPR gene editing cheaper
University of California, Berkeley, researchers have discovered a much cheaper and easier way to target a hot new gene editing tool, CRISPR-Cas9, to cut or label DNA. The CRISPR-Cas9 technique, invented three years ago at UC Berkeley, has taken genomics by storm, with its ability to latch on to a very specific sequence of DNA and cut it, inactivating genes with ease. This has great promise for targeted gene therapy to cure genetic diseases, and for discovering the causes of disease. The...
https://www.biyologlar.com/simple-technology-makes-crispr-gene-editing-cheaper -
Surprising global species shake-up discovered
The diversity of the world's life forms — from corals to carnivores — is under assault. Decades of scientific studies document the fraying of ecosystems and a grim tally of species extinctions due to destroyed habitat, pollution, climate change, invasives and overharvesting. Which makes a recent report in the journal Science rather surprising. Nick Gotelli, a professor at the University of Vermont, with colleagues from Saint Andrews University, Scotland, and the University of Maine,...
https://www.biyologlar.com/surprising-global-species-shake-up-discovered -
New stem cells go back further
One of the obstacles to employing human embryonic stem cells for medical use lies in their very promise: They are born to rapidly differentiate into other cell types.
https://www.biyologlar.com/new-stem-cells-go-back-further -
Rethinking the reef
A new study by biologists at San Diego State University and Scripps Institution of Oceanography shows that inhabited coral islands that engage in commercial fishing dramatically alter their nearby reef ecosystems, disturbing the microbes, corals, algae and fish that call the reef home. The study's lead author, Linda Wegley Kelly, is a postdoctoral scholar in the lab of SDSU virologist Forest Rohwer. For the study, she looked at seawater samples collected from the surfaces of reefs surrounding...
https://www.biyologlar.com/rethinking-the-reef -
Firefly protein enables visualization of roots in soil
Plants form a vast network of below-ground roots that search soil for needed resources. The structure and function of this root network can be highly adapted to particular environments such as desert soils where plants like Mesquite develop tap roots capable of digging 50 meters deep to capture precious water resources. Excavation of root systems reveals these kinds of adaptations but is laborious, time consuming, and does not provide information on how growing roots behave. A new imaging tool...
https://www.biyologlar.com/firefly-protein-enables-visualization-of-roots-in-soil -
Scientists discover an on-off switch for aging cells
Scientists at the Salk Institute have discovered an on-and-off "switch" in cells that may hold the key to healthy aging. This switch points to a way to encourage healthy cells to keep dividing and generating, for example, new lung or liver tissue, even in old age. In our bodies, newly divided cells constantly replenish lungs, skin, liver and other organs. However, most human cells cannot divide indefinitely–with each division, a cellular timekeeper at the ends of chromosomes shortens. When...
https://www.biyologlar.com/scientists-discover-an-on-off-switch-for-aging-cells -
Signs of deforestation in Brazil
Multiple fires are visible in in this image of the Para and Mato Grosso states of Brazil. Many of these were most likely intentionally set in order to deforest the land. Deforestation is the removal of a forest or stand of trees where the land is thereafter converted to a nonforest use. Examples of deforestation include conversion of forestland to farms, ranches, or urban use. The herringbone-patterned tan lines cutting through the dark green of the Amazon Rainforest in the middle of the image...
https://www.biyologlar.com/signs-of-deforestation-in-brazil -
Genome-wide search reveals new genes involved in long-term memory
A new study has identified genes involved in long-term memory in the worm as part of research aimed at finding ways to retain cognitive abilities during aging. The study, which was published in the journal Neuron, identified more than 750 genes involved in long-term memory, including many that had not been found previously and that could serve as targets for future research, said senior author Coleen Murphy, an associate professor of molecular biology and the Lewis-Sigler Institute for...
https://www.biyologlar.com/genome-wide-search-reveals-new-genes-involved-in-long-term-memory -
Long-term changes in dead wood reveal new forest dynamics
Healthy forest ecosystems need dead wood to provide important habitat for birds and mammals, but there can be too much of a good thing when dead wood fuels severe wildfires. A scientist with the U.S. Forest Service's Pacific Southwest Research Station (PSW) compared historic and recent data from a forest in California's central Sierra Nevada region to determine how logging and fire exclusion have changed the amounts and sizes of dead wood over time. Results were recently published in Forest...
https://www.biyologlar.com/long-term-changes-in-dead-wood-reveal-new-forest-dynamics -
Detecting HIV diagnostic antibodies with DNA nanomachines
New research may revolutionize the slow, cumbersome and expensive process of detecting the antibodies that can help with the diagnosis of infectious and auto-immune diseases such as rheumatoid arthritis and HIV. An international team of researchers have designed and synthetized a nanometer-scale DNA "machine" whose customized modifications enable it to recognize a specific target antibody. Their new approach, which they described this month in Angewandte Chemie, promises to support the...
https://www.biyologlar.com/detecting-hiv-diagnostic-antibodies-with-dna-nanomachines -
EMBO Conference Series Chemical Biology 2012
Latest News•Registration is open! •Event poster is now available for download Why You Should Attend•SummaryChemical Biology is a quickly growing highly interdisciplinary field, which investigates biological questions by using chemical strategies and tools. It has emerged to become an important and central discipline by itself complementing areas such as medicinal chemistry, pharmacology, cell biology, structural biology and biochemistry. Researchers in Chemical Biology find...
https://www.biyologlar.com/embo-conference-series-chemical-biology-2012 -
Functional human liver cells grown in the lab
In new research appearing in the prestigious journal Nature Biotechnology, an international research team led by The Hebrew University of Jerusalem describes a new technique for growing human hepatocytes in the laboratory. This groundbreaking development could help advance a variety of liver-related research and applications, from studying drug toxicity to creating bio-artificial liver support for patients awaiting transplantations. The liver is the largest internal organ in the human body,...
https://www.biyologlar.com/functional-human-liver-cells-grown-in-the-lab -
Restoring vision with stem cells
Age-related macular degeneration (AMRD) could be treated by transplanting photoreceptors produced by the directed differentiation of stem cells, thanks to findings published today by Professor Gilbert Bernier of the University of Montreal and its affiliated Maisonneuve-Rosemont Hospital. ARMD is a common eye problem caused by the loss of cones. Bernier's team has developed a highly effective in vitro technique for producing light sensitive retina cells from human embryonic stem cells. "Our...
https://www.biyologlar.com/restoring-vision-with-stem-cells -
Brazilian beef industry moves to reduce its destruction of rain forests
Expansion of cattle pastures has led to the destruction of huge swaths of rain forest in Brazil, home to the world's largest herd of commercial beef cattle. But a new study led by the University of Wisconsin-Madison's Holly Gibbs shows that market-driven "zero deforestation agreements" have dramatically influenced the behavior of ranchers and the slaughterhouses to which they sell. Publishing today [May 12, 2015] in the journal Conservation Letters, the research team - including other...
https://www.biyologlar.com/brazilian-beef-industry-moves-to-reduce-its-destruction-of-rain-forests -
Great Barrier Reef marine reserves combat coral disease
A new and significant role for marine reserves on the Great Barrier Reef has been revealed, with researchers finding the reserves reduce the prevalence of coral diseases. It's been known for some time that marine reserves are important for maintaining and enhancing fish stocks, but this is the first time marine reserves have been shown to enhance coral health on the Great Barrier Reef. Researchers from the ARC Centre of Excellence for Coral Reef Studies at James Cook University found that...
https://www.biyologlar.com/great-barrier-reef-marine-reserves-combat-coral-disease -
Discovery of an unexpected function of a protein linked to neurodegenerative diseases
Until today, the proteins known as ubiquitin receptors have been associated mainly with protein degradation, a basic cell cleaning process. A new function now described for the protein dDsk2 by the team headed by Ferran Azorín, group leader at the Institute for Research in Biomedicine (IRB Barcelona) and CSIC research professor, links ubiquitin receptors for the first time with the regulation of gene expression. This discovery, published today in Nature Communications, opens up a double...
https://www.biyologlar.com/discovery-of-an-unexpected-function-of-a-protein-linked-to-neurodegenerative-diseases -
Discovery of an unexpected function of a protein linked to neurodegenerative diseases
Until today, the proteins known as ubiquitin receptors have been associated mainly with protein degradation, a basic cell cleaning process. A new function now described for the protein dDsk2 by the team headed by Ferran Azorín, group leader at the Institute for Research in Biomedicine (IRB Barcelona) and CSIC research professor, links ubiquitin receptors for the first time with the regulation of gene expression. This discovery, published today in Nature Communications, opens up a double...
https://www.biyologlar.com/discovery-of-an-unexpected-function-of-a-protein-linked-to-neurodegenerative-diseases -
Bering Sea hotspot for corals and sponges
North of the Aleutian Islands, submarine canyons in the cold waters of the eastern Bering Sea contain a highly productive "green belt" that is home to deep-water corals as well as a plethora of fish and marine mammals. Situated along the continental slope, the area also supports a thriving -- but potentially environmentally damaging -- bottom-trawling fishing industry that uses large weighted nets dragged across the seafloor to scoop up everything in their path. A new study, conducted by...
https://www.biyologlar.com/bering-sea-hotspot-for-corals-and-sponges -
Shiny fish skin inspires nanoscale light reflectors
A nature-inspired method to model the reflection of light from the skin of silvery fish and other organisms may be possible, according to Penn State researchers. Such a technique may be applicable to developing better broadband reflectors and custom multi-spectral filters for a wide variety of applications, including advanced optical coatings for glass, laser protection, infrared imaging systems, optical communication systems and photovoltaics, according to Douglas Werner, John L. and...
https://www.biyologlar.com/shiny-fish-skin-inspires-nanoscale-light-reflectors -
Researchers build molecule that could significantly reduce brain damage in stroke victims
Research teams separated by 14 hours and 9,000 miles have collaborated to advance prospective treatment for the world's second-leading cause of death. University of Nebraska-Lincoln chemists partnered with medical researchers from the National University of Singapore to develop a molecule that can inhibit an enzyme linked with the onset of stroke. Most strokes occur when a disruption of blood flow prevents oxygen and glucose from reaching brain tissue, ultimately killing neurons and other...
https://www.biyologlar.com/researchers-build-molecule-that-could-significantly-reduce-brain-damage-in-stroke-victims -
Perfecting a viral pack mule
Viruses aren't always bad. In fact, scientists can harness the capabilities of some viruses for good--modifying the viruses to carry drug molecules, for example. One useful virus has been cowpea mosaic virus (CPMV), a plant pathogen that can be modified to aid in tumor detection and even chemotherapy. In a new study, published online ahead of print in the journal Structure, researchers at The Scripps Research Institute (TSRI) report that, based on its structure, a hollowed-out version of CPMV...
https://www.biyologlar.com/perfecting-a-viral-pack-mule -
Mantis shrimp inspires next generation of ultra-strong materials
This is the herringbone structure of the outer layer (impact region) of the mantis shrimp dactyl club.
https://www.biyologlar.com/mantis-shrimp-inspires-next-generation-of-ultra-strong-materials -
Mantis shrimp inspires next generation of ultra-strong materials
This is the herringbone structure of the outer layer (impact region) of the mantis shrimp dactyl club.
https://www.biyologlar.com/mantis-shrimp-inspires-next-generation-of-ultra-strong-materials -
Why human egg cells don't age well
When egg cells form with an incorrect number of chromosomes--a problem that increases with age--the result is usually a miscarriage or a genetic disease such as Down syndrome. Now, researchers at the RIKEN Center for Developmental Biology in Japan have used a novel imaging technique to pinpoint a significant event that leads to these types of age-related chromosomal errors. Published in Nature Communications, the study shows that as egg cells mature in older women, paired copies of matching...
https://www.biyologlar.com/why-human-egg-cells-dont-age-well -
Stem cell transplant from young to old can heal stomach ulcers
Bethesda, MD (June 16, 2016) -- Basic and translational research paves the way for breakthroughs that can ultimately change patient care. Three new studies from Cellular and Molecular Gastroenterology and Hepatology (CMGH) -- AGA's basic and translational open-access journal -- provide a glimpse into future treatment strategies for stomach ulcers, inflammatory bowel disease and alcoholic liver disease. Please find summaries below. To speak with the journal authors, please email...
https://www.biyologlar.com/stem-cell-transplant-from-young-to-old-can-heal-stomach-ulcers -
Brain scans show birds of a feather do flock together
The hottest hairstyle, the latest extreme sport, the newest viral stunt -- trends happen for a reason and now scientists have a better understanding of why. In a study using functional magnetic resonance imaging, Virginia Tech Carilion Research Institute scientists found that our inherent risk-taking preferences affect how we view and act on information from other people. The brain scans showed that study participants increased their perceived value of a gamble after seeing other people take...
https://www.biyologlar.com/brain-scans-show-birds-of-a-feather-do-flock-together -
New procedure allows long-term culturing of adult stem cells
A new procedure developed at Massachusetts General Hospital (MGH) may revolutionize the culturing of adult stem cells. In their report that has been published online prior to its appearance in the August 6 issue of Cell Stem Cell, the team describes generating and expanding airway stem cells from the sorts of tissue samples collected during routine treatment of lung disorders. The overall approach appears applicable to several other tissue types, including skin and the linings of the...
https://www.biyologlar.com/new-procedure-allows-long-term-culturing-of-adult-stem-cells -
Watching the luminescent gene switch
The system consists of two newly developed programs that automatically identify the 3-D positions of target areas based on the signals from the scintillators (shown as white dots), and determine...
https://www.biyologlar.com/watching-the-luminescent-gene-switch -
Watching the luminescent gene switch
The system consists of two newly developed programs that automatically identify the 3-D positions of target areas based on the signals from the scintillators (shown as white dots), and determine...
https://www.biyologlar.com/watching-the-luminescent-gene-switch -
How our gut changes across the life course
Scientists and clinicians on the Norwich Research Park have carried out the first detailed study of how our intestinal tract changes as we age, and how this determines our overall health. As well as digesting food, the gut plays a central role in programming our immune system, and provides an effective barrier to bacteria that could make us ill. In particular, immune cells that line the gut work to maintain the integrity of the barrier, as well as maintaining a balance that provides a healthy...
https://www.biyologlar.com/how-our-gut-changes-across-the-life-course -
Gene fuels age-related obesity and diabetes
Practically everyone gets fatter as they get older, but some people can blame their genes for the extra padding. Researchers have shown that two different mutations in a gene called ankyrin-B cause cells to suck up glucose faster than normal, fattening them up and eventually triggering the type of diabetes linked to obesity. The more severe of the two mutations, called R1788W, is carried by nearly one million Americans. The milder mutation, known as L1622I, is shared by seven percent of the...
https://www.biyologlar.com/gene-fuels-age-related-obesity-and-diabetes -
Embryonic gene Nanog reverses aging in adult stem cells
The images above show, from left to right, functioning stem cells, stem cells no longer functioning due to Hutchinson-Gilford Progeria syndrome (HGPS), and stem cells previously not functioning
https://www.biyologlar.com/embryonic-gene-nanog-reverses-aging-in-adult-stem-cells -
Embryonic gene Nanog reverses aging in adult stem cells
The images above show, from left to right, functioning stem cells, stem cells no longer functioning due to Hutchinson-Gilford Progeria syndrome (HGPS), and stem cells previously not functioning
https://www.biyologlar.com/embryonic-gene-nanog-reverses-aging-in-adult-stem-cells -
Quantum dots with impermeable shell: A powerful tool for nanoengineering
Images of ZnO quantum dots prepared by the Institute of Physical Chemistry of the Polish Academy of Sciences in Warsaw, taken by transmission electron microscopy. False colors.
https://www.biyologlar.com/quantum-dots-with-impermeable-shell-a-powerful-tool-for-nanoengineering -
Quantum dots with impermeable shell: A powerful tool for nanoengineering
Images of ZnO quantum dots prepared by the Institute of Physical Chemistry of the Polish Academy of Sciences in Warsaw, taken by transmission electron microscopy. False colors.
https://www.biyologlar.com/quantum-dots-with-impermeable-shell-a-powerful-tool-for-nanoengineering -
Missing link found between brain, immune system -- with major disease implications
Vessels directly connecting brain, lymphatic system exist despite decades of doctrine that they don't Finding may have substantial implications for major neurological diseases Game-changing discovery opens new areas of research, transforms existing ones Major gap in understanding of the human body revealed 'They'll have to change the textbooks' CHARLOTTESVILLE, Va., June 1, 2015 - In a stunning discovery that overturns decades of textbook teaching, researchers at the University of...
https://www.biyologlar.com/missing-link-found-between-brain-immune-system-with-major-disease-implications -
Legions of nanorobots target cancerous tumors with precision
The legions of nanorobotic agents are actually composed of more than 100 million flagellated bacteria
https://www.biyologlar.com/legions-of-nanorobots-target-cancerous-tumors-with-precision -
Legions of nanorobots target cancerous tumors with precision
The legions of nanorobotic agents are actually composed of more than 100 million flagellated bacteria
https://www.biyologlar.com/legions-of-nanorobots-target-cancerous-tumors-with-precision -
Alert to biologists: Ribosomes can translate the 'untranslated region' of messenger RNA
In what appears to be an unexpected challenge to a long-accepted fact of biology, Johns Hopkins researchers say they have found that ribosomes -- the molecular machines in all cells that build proteins -- can sometimes do so even within the so-called untranslated regions of the ribbons of genetic material known as messenger RNA (mRNA). "This is an exciting find that generates a whole new set of questions for researchers," says Rachel Green, Ph.D., a Howard Hughes Medical Institute investigator...
https://www.biyologlar.com/alert-to-biologists-ribosomes-can-translate-the-untranslated-region-of-messenger-rna -
New mechanisms of self-organization in living cells
Chromosome is a structure inside the cell nucleus that carries a large part of the genetic information and is responsible for its storage, transfer and implementation. Chromosome is formed from a very long DNA molecule - a double chain of a plurality of genes. Given that the diameter of the cell nucleus is usually around hundredth of a millimeter or even less, while the total length of DNA constituting human genome is about two meters, it is clear that DNA must be packaged very...
https://www.biyologlar.com/new-mechanisms-of-self-organization-in-living-cells -
Scientists solve mystery behind earthworm digestion
Scientists have discovered how earthworms can digest plant material, such as fallen leaves, that would defeat most other herbivores. Earthworms are responsible for returning the carbon locked inside dead plant material back into the ground. They drag fallen leaves and other plant material down from the surface and eat them, enriching the soil, and they do this in spite of toxic chemicals produced by plants to deter herbivores. The scientists, led by Dr Jake Bundy and Dr Manuel Liebeke from...
https://www.biyologlar.com/scientists-solve-mystery-behind-earthworm-digestion -
DNA research offers clues on cell mutation
A team of researchers from Colorado State University has been studying DNA damage in living cells to learn more about how genetic abnormalities arise. It has long been known that DNA molecules in every cell get constantly damaged by things from the outside environment, like sunlight, cigarette smoke and radiation. However, more recently researchers have discovered that sources from within the cell itself can sometimes be even more damaging. DNA, or deoxyribonucleic acid, is found in the...
https://www.biyologlar.com/dna-research-offers-clues-on-cell-mutation -
DNA research offers clues on cell mutation
A team of researchers from Colorado State University has been studying DNA damage in living cells to learn more about how genetic abnormalities arise. It has long been known that DNA molecules in every cell get constantly damaged by things from the outside environment, like sunlight, cigarette smoke and radiation. However, more recently researchers have discovered that sources from within the cell itself can sometimes be even more damaging. DNA, or deoxyribonucleic acid, is found in the...
https://www.biyologlar.com/dna-research-offers-clues-on-cell-mutation