Toplam 222 içerik listeleniyor
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Building a CRISPR rainbow
CRISPRainbow, a new technology using CRISPR/Cas9 developed by scientists at UMass Medical School, allows researchers to tag and track up to seven different genomic locations in live cells. This labeling system, details of which were published in Nature Biotechnology, will be an invaluable tool for studying the structure of the genome in real time.
https://www.biyologlar.com/building-a-crispr-rainbow-haber-8722 -
Kongo Nehri Balıklarının Hızlı Evrimi
Fotoğrafta bir çift akvaryum çiklet balığı türü olan Telegramma brichardi bulunmaktadır. Fotoğraf:Oliver Lucanus
https://www.biyologlar.com/kongo-nehri-baliklarinin-hizli-evrimi -
Kongo Nehri Balıklarının Hızlı Evrimi
Fotoğrafta bir çift akvaryum çiklet balığı türü olan Telegramma brichardi bulunmaktadır. Fotoğraf:Oliver Lucanus
https://www.biyologlar.com/kongo-nehri-baliklarinin-hizli-evrimi -
Kongo Nehri Balıklarının Hızlı Evrimi
Fotoğrafta bir çift akvaryum çiklet balığı türü olan Telegramma brichardi bulunmaktadır. Fotoğraf:Oliver Lucanus
https://www.biyologlar.com/kongo-nehri-baliklarinin-hizli-evrimi -
Sonuçta o kadar da farklı değiliz; İnsanlardaki hücreler ve sağlam mikroplar ortak bir atayı paylaşıyor
Bir araştırma ekibi, arkeal ve ökaryotik hücrelerin genetik materyalini nasıl paketlediğini ve depoladıklarını gösteren çarpıcı paralellikler buldu. Credit: Santangelo and Luger Labs
https://www.biyologlar.com/sonucta-o-kadar-da-farkli-degiliz-insanlardaki-hucreler-ve-saglam-mikroplar-ortak-bir-atayi-paylasiyor -
The Genetic Structure of Anatolia: From the Neolithic to the Oghuz Migrations
Anatolia has witnessed many migrations and has been home to a variety of civilizations. The increasing availability of ancient DNA samples from different periods and cultures makes it now possible to examine the genetic changes that have taken place in Anatolia since the Neolithic. The ancient DNA revolution has already dispelled many myths, but myths and legends die hard. Some of the more persistent ones concern the impact of the last migration wave to hit Anatolia, marked by the arrival of...
https://www.biyologlar.com/the-genetic-structure-of-anatolia-from-the-neolithic-to-the-oghuz-migrations -
Y Kromozomu
Bütün insanlarda X veya Y kromozomlarından birisi mutlaka bulunurken, kadınlarda "46, XX"; erkeklerde "46, XY" normal karyotip olarak bulunur.
https://www.biyologlar.com/y-kromozomu-1 -
New discovery in living cell signaling
A breakthrough discovery into how living cells process and respond to chemical information could help advance the development of treatments for a large number of cancers and other cellular disorders that have been resistant to therapy. An international collaboration of researchers, led by scientists with the U.S. Department of Energy (DOE)'s Lawrence Berkeley National Laboratory (Berkeley Lab) and the University of California (UC) Berkeley, have unlocked the secret behind the activation of the...
https://www.biyologlar.com/new-discovery-in-living-cell-signaling -
Scientists reconstruct ancient impact that dwarfs dinosaur-extinction blast
Picture this: A massive asteroid almost as wide as Rhode Island and about three to five times larger than the rock thought to have wiped out the dinosaurs slams into Earth. The collision punches a crater into the planet's crust that's nearly 500 kilometers (about 300 miles) across: greater than the distance from Washington, D.C. to New York City, and up to two and a half times larger in diameter than the hole formed by the dinosaur-killing asteroid. Seismic waves bigger than any recorded...
https://www.biyologlar.com/scientists-reconstruct-ancient-impact-that-dwarfs-dinosaur-extinction-blast -
Simple technology makes CRISPR gene editing cheaper
University of California, Berkeley, researchers have discovered a much cheaper and easier way to target a hot new gene editing tool, CRISPR-Cas9, to cut or label DNA. The CRISPR-Cas9 technique, invented three years ago at UC Berkeley, has taken genomics by storm, with its ability to latch on to a very specific sequence of DNA and cut it, inactivating genes with ease. This has great promise for targeted gene therapy to cure genetic diseases, and for discovering the causes of disease. The...
https://www.biyologlar.com/simple-technology-makes-crispr-gene-editing-cheaper -
Small molecule acts as on-off switch for nature's antibiotic factory
Scientists have identified the developmental on-off switch for Streptomyces, a group of soil microbes that produce more than two-thirds of the world's naturally derived antibiotic medicines. Their hope now would be to see whether it is possible to manipulate this switch to make nature's antibiotic factory more efficient. The study, appearing August 28 in Cell, found that a unique interaction between a small molecule called cyclic-di-GMP and a larger protein called BldD ultimately controls...
https://www.biyologlar.com/small-molecule-acts-as-on-off-switch-for-natures-antibiotic-factory -
Firefly protein enables visualization of roots in soil
Plants form a vast network of below-ground roots that search soil for needed resources. The structure and function of this root network can be highly adapted to particular environments such as desert soils where plants like Mesquite develop tap roots capable of digging 50 meters deep to capture precious water resources. Excavation of root systems reveals these kinds of adaptations but is laborious, time consuming, and does not provide information on how growing roots behave. A new imaging tool...
https://www.biyologlar.com/firefly-protein-enables-visualization-of-roots-in-soil -
Using DNA origami to build nanodevices of the future
Scientists have been studying ways to use synthetic DNA as a building block for smaller and faster devices. DNA has the advantage of being inherently "coded". Each DNA strand is formed of one of four "codes" that can link to only one complementary code each, thus binding two DNA strands together. Scientists are using this inherent coding to manipulate and "fold" DNA to form "origami nanostructures": extremely small two- and three-dimensional shapes that can then be used as construction material...
https://www.biyologlar.com/using-dna-origami-to-build-nanodevices-of-the-future -
Using DNA origami to build nanodevices of the future
Scientists have been studying ways to use synthetic DNA as a building block for smaller and faster devices. DNA has the advantage of being inherently "coded". Each DNA strand is formed of one of four "codes" that can link to only one complementary code each, thus binding two DNA strands together. Scientists are using this inherent coding to manipulate and "fold" DNA to form "origami nanostructures": extremely small two- and three-dimensional shapes that can then be used as construction material...
https://www.biyologlar.com/using-dna-origami-to-build-nanodevices-of-the-future -
Researchers use human stem cells to create light-sensitive retina in a dish
Using a type of human stem cell, Johns Hopkins researchers say they have created a three-dimensional complement of human retinal tissue in the laboratory, which notably includes functioning photoreceptor cells capable of responding to light, the first step in the process of converting it into visual images.
https://www.biyologlar.com/researchers-use-human-stem-cells-to-create-light-sensitive-retina-in-a-dish -
Brain's on-off thirst switch identified
NEW YORK, NY (January 26, 2015)--Neurons that trigger our sense of thirst--and neurons that turn it off--have been identified by Columbia University Medical Center neuroscientists. The paper was published today in the online edition of Nature. For years, researchers have suspected that thirst is regulated by neurons in the subfornical organ (SFO), in the hypothalamus. But it has been difficult to pinpoint exactly which neurons are involved. "When researchers used electrical current to...
https://www.biyologlar.com/brains-on-off-thirst-switch-identified -
New Science paper calculates magnitude of plastic waste going into the ocean
A plastic grocery bag cartwheels down the beach until a gust of wind spins it into the ocean. In 192 coastal countries, this scenario plays out over and over again as discarded beverage bottles, food wrappers, toys and other bits of plastic make their way from estuaries, seashores and uncontrolled landfills to settle in the world's seas. How much mismanaged plastic waste is making its way from land to ocean has been a decades-long guessing game. Now, the University of Georgia's Jenna Jambeck...
https://www.biyologlar.com/new-science-paper-calculates-magnitude-of-plastic-waste-going-into-the-ocean -
Damaged DNA may stall patrolling molecule to initiate repair
Sites where DNA is damaged may cause a molecule that slides along the DNA strand to scan for damage to slow on its patrol, delaying it long enough to recognize and initiate repair. The finding suggests that the delay itself may be the key that allows the protein molecule to find its target, according to researchers at the University of Illinois at Chicago. Usually, the repair protein zips along quickly, says Anjum Ansari, UIC professor of physics and co-principal investigator on the study,...
https://www.biyologlar.com/damaged-dna-may-stall-patrolling-molecule-to-initiate-repair -
Amniotic stem cells demonstrate healing potential
Rice University and Texas Children's Hospital scientists are using stem cells from amniotic fluid to promote the growth of robust, functional blood vessels in healing hydrogels.
https://www.biyologlar.com/amniotic-stem-cells-demonstrate-healing-potential -
15. Avrupa Biyoteknoloji Kongresi - 15th European Congress on Biotechnology
Biyoteknoloji Dünyası İstanbul’da Bir Araya Geliyo Biyoteknoloji Derneği’nin ev sahipliğinde Zed Etkinlik Yönetimi ve Danışmanlığı tarafından gerçekleştirilecek olan kongre 23-26 Eylül tarihlerinde İstanbul Grand Cevahir Otel’ de biyoteknoloji dünyasını bir araya getiriyo “Bio-crossroads” teması ile 15.kez düzenlenecek olan kongre son olarak, 2009 yılında İspanya’nın Barcelona şehrinde gerçekleştirildi. 108 Kurumsal, 12 binin üzerinde kişisel üyesi...
https://www.biyologlar.com/15-avrupa-biyoteknoloji-kongresi-15th-european-congress-on-biotechnology -
In a role reversal, RNAs proofread themselves
Cold Spring Harbor, NY - Building a protein is a lot like a game of telephone: information is passed along from one messenger to another, creating the potential for errors every step of the way. There are separate, specialized enzymatic machines that proofread at each step, ensuring that the instructions encoded in our DNA are faithfully translated into proteins. Scientists at Cold Spring Harbor Laboratory (CSHL) have uncovered a new quality control mechanism along this path, but in a...
https://www.biyologlar.com/in-a-role-reversal-rnas-proofread-themselves -
Scientists develop mesh that captures oil -- but lets water through
The unassuming piece of stainless steel mesh in a lab at The Ohio State University doesn't look like a very big deal, but it could make a big difference for future environmental cleanups. Water passes through the mesh but oil doesn't, thanks to a nearly invisible oil-repelling coating on its surface. In tests, researchers mixed water with oil and poured the mixture onto the mesh. The water filtered through the mesh to land in a beaker below. The oil collected on top of the mesh, and rolled...
https://www.biyologlar.com/scientists-develop-mesh-that-captures-oil-but-lets-water-through -
Role of telomeres in plant stem cells discovered
The role played by telomeres in mammalian cells has been known for several years. It is also known that these non-coding DNA sequences, which are found at the ends of the chromosomes, protect them and are necessary to ensure correct cell division.
https://www.biyologlar.com/role-of-telomeres-in-plant-stem-cells-discovered -
Fishing impacts on the Great Barrier Reef
New research shows that fishing is having a significant impact on the make-up of fish populations of the Great Barrier Reef. It's long been known that environmental impacts such as climate change and pollution are amongst the drivers of change on the Great Barrier Reef. Now researchers from the ARC Centre of Excellence for Coral Reef Studies (Coral CoE) at James Cook University have found that removing predatory fish such as coral trout and snapper, through fishing, causes significant changes...
https://www.biyologlar.com/fishing-impacts-on-the-great-barrier-reef -
EMBO Conference Series Chemical Biology 2012
Latest News•Registration is open! •Event poster is now available for download Why You Should Attend•SummaryChemical Biology is a quickly growing highly interdisciplinary field, which investigates biological questions by using chemical strategies and tools. It has emerged to become an important and central discipline by itself complementing areas such as medicinal chemistry, pharmacology, cell biology, structural biology and biochemistry. Researchers in Chemical Biology find...
https://www.biyologlar.com/embo-conference-series-chemical-biology-2012 -
Broad, MIT scientists overcome key CRISPR-Cas9 genome editing hurdle
Researchers at the Broad Institute of MIT and Harvard and the McGovern Institute for Brain Research at MIT have engineered changes to the revolutionary CRISPR-Cas9 genome editing system that significantly cut down on "off-target" editing errors. The refined technique addresses one of the major technical issues in the use of genome editing. The CRISPR-Cas9 system works by making a precisely targeted modification in a cell's DNA. The protein Cas9 alters the DNA at a location that is specified by...
https://www.biyologlar.com/broad-mit-scientists-overcome-key-crispr-cas9-genome-editing-hurdle -
Sofra Tuzu
Bu sayımızda, ayın fotoğrafı köşemizde, hepimizin yakından tanıdığı bir madde var: Sofra Tuzu, ya da bilimsel adıyla Sodyum Klorür ( NaCl). Fotoğraf: Cüneyt ÖzdaşMakine: Canon 7DLens: Canon MP-E65Tarih: 30 Mayıs 2012 Sofra tuzu, ya da Sodyum Klorür, her ne kadar gözümüze toz gibi görünse de, aslında küp şeklindeki küçük granüllerden oluşuyor. Softa tuzunun bu kübik yapısı, NaCl bileşiğinin kristalize yapısından kaynaklanıyor. Tipik bir iyonik...
https://www.biyologlar.com/sofra-tuzu -
How an RNA gene silences a whole chromosome
Researchers at Caltech have discovered how an abundant class of RNA genes, called long non-coding RNAs (lncRNAs, pronounced link RNAs) can regulate key genes. By studying an important lncRNA, called Xist, the scientists identified how this RNA gathers a group of proteins and ultimately prevents women from having an extra functional X-chromosome--a condition in female embryos that leads to death in early development. These findings mark the first time that researchers have uncovered the detailed...
https://www.biyologlar.com/how-an-rna-gene-silences-a-whole-chromosome -
Discovery of an unexpected function of a protein linked to neurodegenerative diseases
Until today, the proteins known as ubiquitin receptors have been associated mainly with protein degradation, a basic cell cleaning process. A new function now described for the protein dDsk2 by the team headed by Ferran Azorín, group leader at the Institute for Research in Biomedicine (IRB Barcelona) and CSIC research professor, links ubiquitin receptors for the first time with the regulation of gene expression. This discovery, published today in Nature Communications, opens up a double...
https://www.biyologlar.com/discovery-of-an-unexpected-function-of-a-protein-linked-to-neurodegenerative-diseases -
Discovery of an unexpected function of a protein linked to neurodegenerative diseases
Until today, the proteins known as ubiquitin receptors have been associated mainly with protein degradation, a basic cell cleaning process. A new function now described for the protein dDsk2 by the team headed by Ferran Azorín, group leader at the Institute for Research in Biomedicine (IRB Barcelona) and CSIC research professor, links ubiquitin receptors for the first time with the regulation of gene expression. This discovery, published today in Nature Communications, opens up a double...
https://www.biyologlar.com/discovery-of-an-unexpected-function-of-a-protein-linked-to-neurodegenerative-diseases -
Shiny fish skin inspires nanoscale light reflectors
A nature-inspired method to model the reflection of light from the skin of silvery fish and other organisms may be possible, according to Penn State researchers. Such a technique may be applicable to developing better broadband reflectors and custom multi-spectral filters for a wide variety of applications, including advanced optical coatings for glass, laser protection, infrared imaging systems, optical communication systems and photovoltaics, according to Douglas Werner, John L. and...
https://www.biyologlar.com/shiny-fish-skin-inspires-nanoscale-light-reflectors -
Lab experiments question popular measure of ancient ocean temperatures
Understanding the planet's history is crucial if we are to predict its future. While some records are preserved in ice cores or tree rings, other records of the climate's ancient past are buried deep in the seafloor. An increasingly popular method to deduce historic sea surface temperatures uses sediment-entombed bodies of marine archaea, one of Earth's most ancient and resilient creatures, as a 150-million-year record of ocean temperatures. While other measures have gaps, this one is...
https://www.biyologlar.com/lab-experiments-question-popular-measure-of-ancient-ocean-temperatures -
Genetically modified E. coli pump out morphine precursor
A common gut microbe could soon be offering us pain relief. Japanese bioengineers have tweaked Escherichia coli genes so that they pump out thebaine, a morphine precursor that can be modified to make painkillers. The genetically modified E. coli produces 300 times more thebaine with minimal risk of unregulated use compared to a recently developed method involving yeast. "Morphine has a complex molecular structure; because of this, the production of morphine and similar painkillers is expensive...
https://www.biyologlar.com/genetically-modified-e-coli-pump-out-morphine-precursor -
Odd histone helps suppress jumping genes in stem cells, study says
A family of proteins known as histones provides support and structure to DNA, but for years, scientists have been puzzling over occasional outliers among these histones, which appear to exist for specific, but often mysterious reasons. Now, researchers have uncovered a new purpose for one such histone variant: preventing genetic mutations by keeping certain so-called "jumping genes" in place. This research, which began at Rockefeller University and was published May 4 in Nature, reveals a...
https://www.biyologlar.com/odd-histone-helps-suppress-jumping-genes-in-stem-cells-study-says -
Combining adult stem cells with hormone may speed bone fracture healing
A combination of adult stem cells and parathyroid hormone significantly increased new bone formation in laboratory animals and may speed the healing process for human bone fractures caused by osteoporosis, a new study shows. The study is published online by Molecular Therapy, a peer-reviewed journal in the Nature Publishing Group. Researchers used a combination of mesenchymal stem cells, which are derived from bone marrow taken from adults, and parathyroid hormone, also called PTH, which...
https://www.biyologlar.com/combining-adult-stem-cells-with-hormone-may-speed-bone-fracture-healing -
Nerve cells use each other as maps
When nerve cells form in an embryo they do not start off in the right place but have to be guided to their final position by navigating a kind of molecular and cellular "map" in order to function properly. In a recent research study published in Nature Communications neurobiologist Sara Wilson, Umeå University, found that during embryonic development different parts of the nerve cell are important for guiding other nerve cells into their physical positions. "We found nerve cells do this in...
https://www.biyologlar.com/nerve-cells-use-each-other-as-maps -
Researchers build molecule that could significantly reduce brain damage in stroke victims
Research teams separated by 14 hours and 9,000 miles have collaborated to advance prospective treatment for the world's second-leading cause of death. University of Nebraska-Lincoln chemists partnered with medical researchers from the National University of Singapore to develop a molecule that can inhibit an enzyme linked with the onset of stroke. Most strokes occur when a disruption of blood flow prevents oxygen and glucose from reaching brain tissue, ultimately killing neurons and other...
https://www.biyologlar.com/researchers-build-molecule-that-could-significantly-reduce-brain-damage-in-stroke-victims -
Perfecting a viral pack mule
Viruses aren't always bad. In fact, scientists can harness the capabilities of some viruses for good--modifying the viruses to carry drug molecules, for example. One useful virus has been cowpea mosaic virus (CPMV), a plant pathogen that can be modified to aid in tumor detection and even chemotherapy. In a new study, published online ahead of print in the journal Structure, researchers at The Scripps Research Institute (TSRI) report that, based on its structure, a hollowed-out version of CPMV...
https://www.biyologlar.com/perfecting-a-viral-pack-mule -
Griffith uses 3-D tissue engineering to revolutionize dental disease
The discomfort and stigma of loose or missing teeth could be a thing of the past as Griffith University researchers pioneer the use of 3D bioprinting to replace missing teeth and bone. The three-year study, which has been granted a National Health and Medical Research Council Grant of $650,000, is being undertaken by periodontist Professor Saso Ivanovski from Griffith's Menzies Health Institute Queensland. As part of an Australian first, Professor Ivanovski and his team are using the latest...
https://www.biyologlar.com/griffith-uses-3-d-tissue-engineering-to-revolutionize-dental-disease -
Small molecules change biological clock rhythm
A team of chemists and biologists at the Institute of Transformative Bio-Molecules (ITbM), Nagoya University have succeeded in finding new molecules that change the circadian rhythm in mammals by applying synthetic chemistry methods, which makes use of highly selective metal catalysts. Most living organisms have a biological clock with an approximately 24-hour circadian rhythm, which regulates important body functions such as sleep/wake cycles, hormone secretion, and metabolism. Disruption of...
https://www.biyologlar.com/small-molecules-change-biological-clock-rhythm -
Researchers use single molecule of DNA to create world's smallest diode
Researchers at the University of Georgia and at Ben-Gurion University in Israel have demonstrated for the first time that nanoscale electronic components can be made from single DNA molecules. Their study, published in the journal Nature Chemistry, represents a promising advance in the search for a replacement for the silicon chip. The finding may eventually lead to smaller, more powerful and more advanced electronic devices, according to the study's lead author, Bingqian Xu. "For 50 years,...
https://www.biyologlar.com/researchers-use-single-molecule-of-dna-to-create-worlds-smallest-diode -
Researchers use single molecule of DNA to create world's smallest diode
Researchers at the University of Georgia and at Ben-Gurion University in Israel have demonstrated for the first time that nanoscale electronic components can be made from single DNA molecules. Their study, published in the journal Nature Chemistry, represents a promising advance in the search for a replacement for the silicon chip. The finding may eventually lead to smaller, more powerful and more advanced electronic devices, according to the study's lead author, Bingqian Xu. "For 50 years,...
https://www.biyologlar.com/researchers-use-single-molecule-of-dna-to-create-worlds-smallest-diode -
Spider and centipede venom evolved from insulin-like hormone
Funnel-web spider venom contains powerful neurotoxins that instantly paralyze prey (usually insects). Millions of years ago, however, this potent poison was just a hormone that helped ancestors of these spiders regulate sugar metabolism, similar to the role of insulin in humans. Surprisingly, this hormone's weaponization--described on June 11 in the journal Structure--occurred in arachnids as well as centipedes, but in different ways. Researchers at the University of Queensland in Australia...
https://www.biyologlar.com/spider-and-centipede-venom-evolved-from-insulin-like-hormone -
These gigantic whales have nerves like bungee cords
Nerves aren't known for being stretchy. In fact, "nerve stretch injury" is a common form of trauma in humans. But researchers reporting in
https://www.biyologlar.com/these-gigantic-whales-have-nerves-like-bungee-cords -
A microtubule 'roadway' in the retina helps provide energy for vision
Researchers have discovered a thick band of microtubules in certain neurons in the retina that they believe acts as a transport road for mitochondria that help provide energy required for visual processing. The findings appear in the July issue of The Journal of General Physiology. The retina is a layer of tissue in the back of the eye that converts light into nerve impulses. The retina contains small, specialized neurons called bipolar cells that transmit information from light-sensitive...
https://www.biyologlar.com/a-microtubule-roadway-in-the-retina-helps-provide-energy-for-vision -
Scientists discover oldest plant root stem cells
Scientists at Oxford University have discovered the oldest known population of plant root stem cells in a 320 million-year-old fossil.
https://www.biyologlar.com/scientists-discover-oldest-plant-root-stem-cells -
Mantis shrimp inspires next generation of ultra-strong materials
This is the herringbone structure of the outer layer (impact region) of the mantis shrimp dactyl club.
https://www.biyologlar.com/mantis-shrimp-inspires-next-generation-of-ultra-strong-materials -
Mantis shrimp inspires next generation of ultra-strong materials
This is the herringbone structure of the outer layer (impact region) of the mantis shrimp dactyl club.
https://www.biyologlar.com/mantis-shrimp-inspires-next-generation-of-ultra-strong-materials -
Hybrid cells cause chaos around cancers
Rice University researchers have built a simulation to show how cancerous tumors manipulate blood-vessel growth for their own benefit. Like all cells, those in tumors need access to the body's fine network of blood vessels to bring them oxygen and carry away waste. Tumors have learned to game the process called angiogenesis in which new vessels sprout from existing ones, like branches from a tree. But some details have been hidden until now. The ability to stop tumors through...
https://www.biyologlar.com/hybrid-cells-cause-chaos-around-cancers -
How our gut changes across the life course
Scientists and clinicians on the Norwich Research Park have carried out the first detailed study of how our intestinal tract changes as we age, and how this determines our overall health. As well as digesting food, the gut plays a central role in programming our immune system, and provides an effective barrier to bacteria that could make us ill. In particular, immune cells that line the gut work to maintain the integrity of the barrier, as well as maintaining a balance that provides a healthy...
https://www.biyologlar.com/how-our-gut-changes-across-the-life-course