Toplam 120 içerik listeleniyor
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The genetic evolution of Zika virus
This is a phylogenetic tree constructed from nucleotide data from 41 viral complete ORF sequences of ZIKV strains An analysis comparing the individual differences between over 40 strains of Zika virus (30 isolated from humans, 10 from mosquitoes, and 1 from monkeys) has identified significant changes in both amino acid and nucleotide sequences during the past half-century. The data, published April 15 in Cell Host & Microbe, support a strong divergence between the Asian and African lineages as...
https://www.biyologlar.com/the-genetic-evolution-of-zika-virus-haber-8121 -
Fossil find reveals just how big carnivorous dinosaur may have grown
Here is an artist's drawing of the abelisaur. An unidentified fossilised bone in a museum has revealed the size of a fearsome abelisaur and may have solved a hundred-year old puzzle.
https://www.biyologlar.com/fossil-find-reveals-just-how-big-carnivorous-dinosaur-may-have-grown-haber-8721 -
Pancreas stem cell discovery may lead to new diabetes treatments
Stem cells in the adult pancreas have been identified that can be turned into insulin producing cells, a finding that means people with type 1 diabetes might one day be able to regenerate their own insulin-producing cells. The discovery was made by scientists from the Walter and Eliza Hall Institute and provides further evidence that stem cells don't only occur in the embryo. The ability to produce the hormone insulin is crucial for controlling blood sugar (glucose) levels. In people with...
https://www.biyologlar.com/pancreas-stem-cell-discovery-may-lead-to-new-diabetes-treatments -
22 . Kromozom
İnsanlar normalde her hücrede 23 çifte bölünmüş 46 kromozoma sahiptir. Her ebeveynden miras alınan bir kopya olmak üzere 22 numaralı kromozomun iki kopyası, çiftlerden birini oluşturur. İnsan genomunda toplamda 23, otozom olarak 22 adet bulunan kromozom çiftlerinden biridir. Normal insan genomundaki tüm otozomlar için geçerli olduğu gibi, kromozom 22 de iki kopya halinde bulunur. İkinci en küçük insan kromozomu olan 22. kromozom , yaklaşık 49 milyon baz çiftiyle,...
https://www.biyologlar.com/22-kromozom -
Small molecule acts as on-off switch for nature's antibiotic factory
Scientists have identified the developmental on-off switch for Streptomyces, a group of soil microbes that produce more than two-thirds of the world's naturally derived antibiotic medicines. Their hope now would be to see whether it is possible to manipulate this switch to make nature's antibiotic factory more efficient. The study, appearing August 28 in Cell, found that a unique interaction between a small molecule called cyclic-di-GMP and a larger protein called BldD ultimately controls...
https://www.biyologlar.com/small-molecule-acts-as-on-off-switch-for-natures-antibiotic-factory -
Enzyme controlling metastasis of breast cancer identified
Researchers at the University of California, San Diego School of Medicine have identified an enzyme that controls the spread of breast cancer. The findings, reported in the current issue of PNAS, offer hope for the leading cause of breast cancer mortality worldwide. An estimated 40,000 women in America will die of breast cancer in 2014, according to the American Cancer Society. "The take-home message of the study is that we have found a way to target breast cancer metastasis through a pathway...
https://www.biyologlar.com/enzyme-controlling-metastasis-of-breast-cancer-identified -
Rethinking the reef
A new study by biologists at San Diego State University and Scripps Institution of Oceanography shows that inhabited coral islands that engage in commercial fishing dramatically alter their nearby reef ecosystems, disturbing the microbes, corals, algae and fish that call the reef home. The study's lead author, Linda Wegley Kelly, is a postdoctoral scholar in the lab of SDSU virologist Forest Rohwer. For the study, she looked at seawater samples collected from the surfaces of reefs surrounding...
https://www.biyologlar.com/rethinking-the-reef -
Genome-wide search reveals new genes involved in long-term memory
A new study has identified genes involved in long-term memory in the worm as part of research aimed at finding ways to retain cognitive abilities during aging. The study, which was published in the journal Neuron, identified more than 750 genes involved in long-term memory, including many that had not been found previously and that could serve as targets for future research, said senior author Coleen Murphy, an associate professor of molecular biology and the Lewis-Sigler Institute for...
https://www.biyologlar.com/genome-wide-search-reveals-new-genes-involved-in-long-term-memory -
Brain's on-off thirst switch identified
NEW YORK, NY (January 26, 2015)--Neurons that trigger our sense of thirst--and neurons that turn it off--have been identified by Columbia University Medical Center neuroscientists. The paper was published today in the online edition of Nature. For years, researchers have suspected that thirst is regulated by neurons in the subfornical organ (SFO), in the hypothalamus. But it has been difficult to pinpoint exactly which neurons are involved. "When researchers used electrical current to...
https://www.biyologlar.com/brains-on-off-thirst-switch-identified -
Wisconsin scientists find genetic recipe to turn stem cells to blood
The ability to reliably and safely make in the laboratory all of the different types of cells in human blood is one key step closer to reality.
https://www.biyologlar.com/wisconsin-scientists-find-genetic-recipe-to-turn-stem-cells-to-blood -
Wheat disease-resistance gene identified, potential to save billions
A gene that can prevent some of the most important wheat diseases has been identified--creating the potential to save more than a billion dollars in lost production in Australia alone each year. In a global collaboration including the University of Sydney's Plant Breeding Institute (PBI), the CSIRO, CIMMYT (Mexico), University of Newcastle, Chinese Academy of Sciences and the Norwegian University of Life Sciences, the gene Lr67 has been identified as providing resistance to three of the most...
https://www.biyologlar.com/wheat-disease-resistance-gene-identified-potential-to-save-billions -
New brain mapping reveals unknown cell types
Using a process known as single cell sequencing, scientists at Karolinska Institutet have produced a detailed map of cortical cell types and the genes active within them. The study, which is published in the journal 'Science', marks the first time this method of analysis has been used on such a large scale on such complex tissue. The team studied over three thousand cells, one at a time, and even managed to identify a number of hitherto unknown types. "If you compare the brain to a fruit...
https://www.biyologlar.com/new-brain-mapping-reveals-unknown-cell-types -
New study shows parrotfish are critical to coral reef island building
As well as being a beautiful species capable of changing its colour, shape and even gender, new research published today shows that parrotfish, commonly found on healthy coral reefs, can also play a pivotal role in providing the sands necessary to build and maintain coral reef islands. The study, based on work in the Maldives and published in the journal Geology, found that parrotfish produced more than 85% of the new sand-grade sediment on the reefs around these reef islands. Reef islands...
https://www.biyologlar.com/new-study-shows-parrotfish-are-critical-to-coral-reef-island-building -
How an RNA gene silences a whole chromosome
Researchers at Caltech have discovered how an abundant class of RNA genes, called long non-coding RNAs (lncRNAs, pronounced link RNAs) can regulate key genes. By studying an important lncRNA, called Xist, the scientists identified how this RNA gathers a group of proteins and ultimately prevents women from having an extra functional X-chromosome--a condition in female embryos that leads to death in early development. These findings mark the first time that researchers have uncovered the detailed...
https://www.biyologlar.com/how-an-rna-gene-silences-a-whole-chromosome -
Unpacking embryonic pluripotency
Researchers at EMBL's European Bioinformatics Institute (EMBL-EBI) and the Wellcome Trust- Medical Research Council Cambridge Stem Cell Institute at the University of Cambridge have identified factors that spark the formation of pluripotent cells.
https://www.biyologlar.com/unpacking-embryonic-pluripotency -
Discovery of an unexpected function of a protein linked to neurodegenerative diseases
Until today, the proteins known as ubiquitin receptors have been associated mainly with protein degradation, a basic cell cleaning process. A new function now described for the protein dDsk2 by the team headed by Ferran Azorín, group leader at the Institute for Research in Biomedicine (IRB Barcelona) and CSIC research professor, links ubiquitin receptors for the first time with the regulation of gene expression. This discovery, published today in Nature Communications, opens up a double...
https://www.biyologlar.com/discovery-of-an-unexpected-function-of-a-protein-linked-to-neurodegenerative-diseases -
Discovery of an unexpected function of a protein linked to neurodegenerative diseases
Until today, the proteins known as ubiquitin receptors have been associated mainly with protein degradation, a basic cell cleaning process. A new function now described for the protein dDsk2 by the team headed by Ferran Azorín, group leader at the Institute for Research in Biomedicine (IRB Barcelona) and CSIC research professor, links ubiquitin receptors for the first time with the regulation of gene expression. This discovery, published today in Nature Communications, opens up a double...
https://www.biyologlar.com/discovery-of-an-unexpected-function-of-a-protein-linked-to-neurodegenerative-diseases -
New GTEx findings show how DNA differences influence gene activity, disease susceptibility
Researchers funded by the National Institutes of Health Genotype-Tissue Expression (GTEx) project have created a new and much-anticipated data resource to help establish how differences in an individual's genomic make-up can affect gene activity and contribute to disease. The new resource will enable scientists to examine the underlying genomics of many different human tissues and cells at the same time, and promises to open new avenues to the study and understanding of human biology. GTEx...
https://www.biyologlar.com/new-gtex-findings-show-how-dna-differences-influence-gene-activity-disease-susceptibility -
Perfecting a viral pack mule
Viruses aren't always bad. In fact, scientists can harness the capabilities of some viruses for good--modifying the viruses to carry drug molecules, for example. One useful virus has been cowpea mosaic virus (CPMV), a plant pathogen that can be modified to aid in tumor detection and even chemotherapy. In a new study, published online ahead of print in the journal Structure, researchers at The Scripps Research Institute (TSRI) report that, based on its structure, a hollowed-out version of CPMV...
https://www.biyologlar.com/perfecting-a-viral-pack-mule -
A quartet of genes controls growth of blood stem cells
An important element in getting blood stem cells to multiply outside the body is to understand which of the approximately 20 000 genes in the human body control their growth. A research team at Lund University in Sweden has studied close to 15 000 of these genes alongside each other. The researchers have succeeded in identifying four key genes which, together, govern the growth and multiplication of the stem cells. The study is now being published in the journal Cell Reports. Every day, over...
https://www.biyologlar.com/a-quartet-of-genes-controls-growth-of-blood-stem-cells -
Clues contained in ancient brain point to the origin of heads in early animals
A new study from the University of Cambridge has identified one of the oldest fossil brains ever discovered - more than 500 million years old - and used it to help determine how heads first evolved in early animals. The results, published today (7 May) in the journal Current Biology, identify a key point in the evolutionary transition from soft to hard bodies in early ancestors of arthropods, the group that contains modern insects, crustaceans and spiders. The study looked at two types of...
https://www.biyologlar.com/clues-contained-in-ancient-brain-point-to-the-origin-of-heads-in-early-animals -
Scientists discover oldest plant root stem cells
Scientists at Oxford University have discovered the oldest known population of plant root stem cells in a 320 million-year-old fossil.
https://www.biyologlar.com/scientists-discover-oldest-plant-root-stem-cells -
Mantis shrimp inspires next generation of ultra-strong materials
This is the herringbone structure of the outer layer (impact region) of the mantis shrimp dactyl club.
https://www.biyologlar.com/mantis-shrimp-inspires-next-generation-of-ultra-strong-materials -
Mantis shrimp inspires next generation of ultra-strong materials
This is the herringbone structure of the outer layer (impact region) of the mantis shrimp dactyl club.
https://www.biyologlar.com/mantis-shrimp-inspires-next-generation-of-ultra-strong-materials -
Breakthrough in scaling up life-changing stem cell production
Scientists have discovered a new method of creating human stem cells which could solve the big problem of the large-scale production needed to fully realise the potential of these remarkable cells for understanding and treating disease.
https://www.biyologlar.com/breakthrough-in-scaling-up-life-changing-stem-cell-production -
Four newly identified genes could improve rice
The GWAS results for genes that influence flowering dates. The known genes Hd1, Hd2, and Hd6 were located, together with two newly-identified genes that also affect flowering dates.
https://www.biyologlar.com/four-newly-identified-genes-could-improve-rice -
Four newly identified genes could improve rice
The GWAS results for genes that influence flowering dates. The known genes Hd1, Hd2, and Hd6 were located, together with two newly-identified genes that also affect flowering dates.
https://www.biyologlar.com/four-newly-identified-genes-could-improve-rice -
Disease that causes blindness in children tied to new gene
Northwestern Medicine and University of Wisconsin-Madison (UW) scientists have identified a gene that causes severe glaucoma in children.
https://www.biyologlar.com/disease-that-causes-blindness-in-children-tied-to-new-gene -
CRISPR gene editing reveals new therapeutic approach for blood disorders
This is a scanning electron micrograph of sickled and other red blood cells.
https://www.biyologlar.com/crispr-gene-editing-reveals-new-therapeutic-approach-for-blood-disorders -
CRISPR gene editing reveals new therapeutic approach for blood disorders
This is a scanning electron micrograph of sickled and other red blood cells.
https://www.biyologlar.com/crispr-gene-editing-reveals-new-therapeutic-approach-for-blood-disorders -
Alert to biologists: Ribosomes can translate the 'untranslated region' of messenger RNA
In what appears to be an unexpected challenge to a long-accepted fact of biology, Johns Hopkins researchers say they have found that ribosomes -- the molecular machines in all cells that build proteins -- can sometimes do so even within the so-called untranslated regions of the ribbons of genetic material known as messenger RNA (mRNA). "This is an exciting find that generates a whole new set of questions for researchers," says Rachel Green, Ph.D., a Howard Hughes Medical Institute investigator...
https://www.biyologlar.com/alert-to-biologists-ribosomes-can-translate-the-untranslated-region-of-messenger-rna -
Eukaryotes: A new timetable of evolution
Contaminated samples have evidently created some confusion in the timetable of life. On the basis of ultra-clean analyses, an international team, including scientists from the Max Planck Institute for Biogeochemistry, has disproved supposed evidence that eukaryotes originated 2.5 to 2.8 billion years ago. In contrast to prokaryotes such as bacteria, eukaryotes have a nucleus. Some researchers thought they had discovered molecular remnants of living organisms in rock samples up to 2.8 billion...
https://www.biyologlar.com/eukaryotes-a-new-timetable-of-evolution -
Deciphering the olfactory receptor code
In animals, numerous behaviors are governed by the olfactory perception of their surrounding world. Whether originating in the nose of a mammal or the antennas of an insect, perception results from the combined activation of multiple receptors located in these organs. Identifying the full repertoire of receptors stimulated by a given odorant would represent a key step in deciphering the code that mediates these behaviors. To this end, a tool that provides a complete olfactory receptor signature...
https://www.biyologlar.com/deciphering-the-olfactory-receptor-code -
Researchers discover how petunias know when to smell good
Good timing is a matter of skill. You would certainly dress up for an afternoon business meeting, but not an evening session of binge-watching Netflix. If you were just a few hours off in your wardrobe timing, your spouse might wonder why you slipped into a stiff business suit to watch "House of Cards." While humans are alone in their struggle to balance work and Netflix, all creatures wrestle with proper timing. With limited resources, organisms are pressed to use time wisely in all aspects...
https://www.biyologlar.com/researchers-discover-how-petunias-know-when-to-smell-good -
Scientists solve mystery behind earthworm digestion
Scientists have discovered how earthworms can digest plant material, such as fallen leaves, that would defeat most other herbivores. Earthworms are responsible for returning the carbon locked inside dead plant material back into the ground. They drag fallen leaves and other plant material down from the surface and eat them, enriching the soil, and they do this in spite of toxic chemicals produced by plants to deter herbivores. The scientists, led by Dr Jake Bundy and Dr Manuel Liebeke from...
https://www.biyologlar.com/scientists-solve-mystery-behind-earthworm-digestion -
Two proteins control the growth of the heart and its adaptation to high blood pressure
Researchers at the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC) have identified how two proteins control the growth of the heart and its adaptation to high blood pressure (hypertension). Lead investigator Dr. Guadalupe Sabio explains that the results, described in Nature Communications, not only increase our understanding of the mechanisms used by cardiac cells to grow and adapt, but could also help in the design of new strategies to treat heart failure caused by...
https://www.biyologlar.com/two-proteins-control-the-growth-of-the-heart-and-its-adaptation-to-high-blood-pressure -
Structure of a hantavirus protein as a promising model for drug design
Bank voles are small rodents that are not dangerous by themselves, but their excreta can contain one of the dangerous hantaviruses. While bank voles are unaffected by the infection, hantaviruses can cause potentially fatal diseases in humans for which no treatments exist. In central and northern Europe, infection is accompanied by fever, headache, or even renal failure. The strain that occurs in East Asia -- the Hantaan virus -- is even more dangerous: up to five percent of infected patients...
https://www.biyologlar.com/structure-of-a-hantavirus-protein-as-a-promising-model-for-drug-design -
First gene linked to temperature sex switch
The sex of many reptile species is set by temperature. New research reported in the journal GENETICS identifies the first gene associated with temperature-dependent sex determination in any reptile.
https://www.biyologlar.com/first-gene-linked-to-temperature-sex-switch -
First gene linked to temperature sex switch
The sex of many reptile species is set by temperature. New research reported in the journal GENETICS identifies the first gene associated with temperature-dependent sex determination in any reptile.
https://www.biyologlar.com/first-gene-linked-to-temperature-sex-switch -
Cells check DNA segregation at the end of their division
The cells in our bodies are constantly dividing. From embryonic development to adult life, cell division is necessary for tissue growth and renewal.
https://www.biyologlar.com/cells-check-dna-segregation-at-the-end-of-their-division -
An enzyme enigma discovered in the abyss
Scientists at the Universities of Bristol and Newcastle have uncovered the secret of the 'Mona Lisa of chemical reactions' - in a bacterium that lives at the bottom of the Pacific Ocean.
https://www.biyologlar.com/an-enzyme-enigma-discovered-in-the-abyss -
An enzyme enigma discovered in the abyss
Scientists at the Universities of Bristol and Newcastle have uncovered the secret of the 'Mona Lisa of chemical reactions' - in a bacterium that lives at the bottom of the Pacific Ocean.
https://www.biyologlar.com/an-enzyme-enigma-discovered-in-the-abyss -
New insights into a virus proteome
The genome encodes the complete information needed by an organism, including that required for protein production. Viruses, which are up to a thousand times smaller than human cells, have considerably smaller genomes. Using a type of herpesvirus as a model system, the scientists of the Max Planck Institute of Biochemistry in Martinsried near Munich and their collaboration partners at the University of California in San Francisco have shown that the genome of this virus contains much more...
https://www.biyologlar.com/new-insights-into-a-virus-proteome -
Hydra can modify its genetic program
Champion of regeneration, the freshwater polyp Hydra is capable of reforming a complete individual from any fragment of its body. It is even able to remain alive when all its neurons have disappeared. Researcher the University of Geneva (UNIGE), Switzerland, have discovered how: cells of the epithelial type modify their genetic program by overexpressing a series of genes, among which some are involved in diverse nervous functions. Studying Hydra cellular plasticity may thus influence research...
https://www.biyologlar.com/hydra-can-modify-its-genetic-program -
Hydra can modify its genetic program
Champion of regeneration, the freshwater polyp Hydra is capable of reforming a complete individual from any fragment of its body. It is even able to remain alive when all its neurons have disappeared. Researcher the University of Geneva (UNIGE), Switzerland, have discovered how: cells of the epithelial type modify their genetic program by overexpressing a series of genes, among which some are involved in diverse nervous functions. Studying Hydra cellular plasticity may thus influence research...
https://www.biyologlar.com/hydra-can-modify-its-genetic-program -
Second contagious form of cancer found in Tasmanian devils
Transmissible cancers -- cancers which can spread between individuals by the transfer of living cancer cells -- are believed to arise extremely rarely in nature.
https://www.biyologlar.com/second-contagious-form-of-cancer-found-in-tasmanian-devils -
Genetic code of red blood cells discovered
Eight days. That's how long it takes for skin cells to reprogram into red blood cells. Researchers at Lund University in Sweden, together with colleagues at Center of Regenerative Medicine in Barcelona, have successfully identified the four genetic keys that unlock the genetic code of skin cells and reprogram them to start producing red blood cells instead. "We have performed this experiment on mice, and the preliminary results indicate that it is also possible to reprogram skin cells from...
https://www.biyologlar.com/genetic-code-of-red-blood-cells-discovered -
Genetic code of red blood cells discovered
Eight days. That's how long it takes for skin cells to reprogram into red blood cells. Researchers at Lund University in Sweden, together with colleagues at Center of Regenerative Medicine in Barcelona, have successfully identified the four genetic keys that unlock the genetic code of skin cells and reprogram them to start producing red blood cells instead. "We have performed this experiment on mice, and the preliminary results indicate that it is also possible to reprogram skin cells from...
https://www.biyologlar.com/genetic-code-of-red-blood-cells-discovered -
A key protein is discovered as essential for malaria parasite transmission to mosquitos
Two teams have independently discovered that a single regulatory protein acts as the master genetic switch that triggers the development of male and female sexual forms (termed gametocytes) of the malaria parasite, solving a long-standing mystery in parasite biology with important implications for human health. The protein, AP2-G, is necessary for activating a set of genes that initiate the development of gametocytes -- the only forms that are infectious to mosquitos. The research also gives...
https://www.biyologlar.com/a-key-protein-is-discovered-as-essential-for-malaria-parasite-transmission-to-mosquitos -
Sociable chimps harbor richer gut microbiomes
Spending time in close contact with others often means risking catching germs and getting sick. But being sociable may also help transmit beneficial microbes, finds a multi-institutional study of gut microbiomes in chimpanzees.
https://www.biyologlar.com/sociable-chimps-harbor-richer-gut-microbiomes