Toplam 113 içerik listeleniyor
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Bird genomes contain 'fossils' of parasites that now infect humans
The researchers found DNA 'fossils' of parasitic nematodes in seven groups of birds (clockwise): trogons, mesites, parrots, hummingbirds, hornbills, manakins, tinamous. In rare instances, DNA is known to have jumped from one species to another. If a parasite's DNA jumps to its host's genome, it could leave evidence of that parasitic interaction that could be found millions of years later -- a DNA 'fossil' of sorts. An international research team led from Uppsala University has discovered a new...
https://www.biyologlar.com/bird-genomes-contain-aposfossils-apos-of-parasites-that-now-infect-humans-haber-8710 -
Tarih öncesi insanlarda Hepatit B virüsü bulunduğu ortaya çıktı
Hepatitis viral partiküllerinin illustrasyonu Kaynak: ISTOCK, SARATHSASIDHARAN
https://www.biyologlar.com/tarih-oncesi-insanlarda-hepatit-b-virusu-bulundugu-ortaya-cikti -
Tarih öncesi insanlarda Hepatit B virüsü bulunduğu ortaya çıktı
Hepatitis viral partiküllerinin illustrasyonu Kaynak: ISTOCK, SARATHSASIDHARAN
https://www.biyologlar.com/tarih-oncesi-insanlarda-hepatit-b-virusu-bulundugu-ortaya-cikti -
Tarih öncesi insanlarda Hepatit B virüsü bulunduğu ortaya çıktı
Hepatitis viral partiküllerinin illustrasyonu Kaynak: ISTOCK, SARATHSASIDHARAN
https://www.biyologlar.com/tarih-oncesi-insanlarda-hepatit-b-virusu-bulundugu-ortaya-cikti -
Simple technology makes CRISPR gene editing cheaper
University of California, Berkeley, researchers have discovered a much cheaper and easier way to target a hot new gene editing tool, CRISPR-Cas9, to cut or label DNA. The CRISPR-Cas9 technique, invented three years ago at UC Berkeley, has taken genomics by storm, with its ability to latch on to a very specific sequence of DNA and cut it, inactivating genes with ease. This has great promise for targeted gene therapy to cure genetic diseases, and for discovering the causes of disease. The...
https://www.biyologlar.com/simple-technology-makes-crispr-gene-editing-cheaper -
New stem cells go back further
One of the obstacles to employing human embryonic stem cells for medical use lies in their very promise: They are born to rapidly differentiate into other cell types.
https://www.biyologlar.com/new-stem-cells-go-back-further -
Genome-wide search reveals new genes involved in long-term memory
A new study has identified genes involved in long-term memory in the worm as part of research aimed at finding ways to retain cognitive abilities during aging. The study, which was published in the journal Neuron, identified more than 750 genes involved in long-term memory, including many that had not been found previously and that could serve as targets for future research, said senior author Coleen Murphy, an associate professor of molecular biology and the Lewis-Sigler Institute for...
https://www.biyologlar.com/genome-wide-search-reveals-new-genes-involved-in-long-term-memory -
How an RNA gene silences a whole chromosome
Researchers at Caltech have discovered how an abundant class of RNA genes, called long non-coding RNAs (lncRNAs, pronounced link RNAs) can regulate key genes. By studying an important lncRNA, called Xist, the scientists identified how this RNA gathers a group of proteins and ultimately prevents women from having an extra functional X-chromosome--a condition in female embryos that leads to death in early development. These findings mark the first time that researchers have uncovered the detailed...
https://www.biyologlar.com/how-an-rna-gene-silences-a-whole-chromosome -
Perfecting a viral pack mule
Viruses aren't always bad. In fact, scientists can harness the capabilities of some viruses for good--modifying the viruses to carry drug molecules, for example. One useful virus has been cowpea mosaic virus (CPMV), a plant pathogen that can be modified to aid in tumor detection and even chemotherapy. In a new study, published online ahead of print in the journal Structure, researchers at The Scripps Research Institute (TSRI) report that, based on its structure, a hollowed-out version of CPMV...
https://www.biyologlar.com/perfecting-a-viral-pack-mule -
Purest yet liver-like cells generated from induced pluripotent stem cells
This image shows induced pluripotent stem cells expressing a characteristic cell surface protein called SSEA4 (green).
https://www.biyologlar.com/purest-yet-liver-like-cells-generated-from-induced-pluripotent-stem-cells -
Purest yet liver-like cells generated from induced pluripotent stem cells
This image shows induced pluripotent stem cells expressing a characteristic cell surface protein called SSEA4 (green).
https://www.biyologlar.com/purest-yet-liver-like-cells-generated-from-induced-pluripotent-stem-cells -
New mechanisms of self-organization in living cells
Chromosome is a structure inside the cell nucleus that carries a large part of the genetic information and is responsible for its storage, transfer and implementation. Chromosome is formed from a very long DNA molecule - a double chain of a plurality of genes. Given that the diameter of the cell nucleus is usually around hundredth of a millimeter or even less, while the total length of DNA constituting human genome is about two meters, it is clear that DNA must be packaged very...
https://www.biyologlar.com/new-mechanisms-of-self-organization-in-living-cells -
Scientists discover protein's starring role in genome stability, and possibly cancer prevention
If you have a soft spot for unsung heroes, you'll love a DNA repair protein called XPG. Scientists from the U.S. Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) discovered that XPG plays a previously unknown and critical role helping to maintain genome stability in human cells. Their findings also raise the possibility that the protein helps prevent breast, ovarian, and other cancers associated with defective BRCA genes. The research, which is published online Jan....
https://www.biyologlar.com/scientists-discover-proteins-starring-role-in-genome-stability-and-possibly-cancer-prevention -
Some bacterial CRISPRs can snip RNA, too
You've probably seen news stories about the highly lauded, much-discussed genome editing system CRISPR/Cas9.
https://www.biyologlar.com/some-bacterial-crisprs-can-snip-rna-too -
Some bacterial CRISPRs can snip RNA, too
You've probably seen news stories about the highly lauded, much-discussed genome editing system CRISPR/Cas9.
https://www.biyologlar.com/some-bacterial-crisprs-can-snip-rna-too -
'Fourth strand' of European ancestry originated with hunter-gatherers isolated by Ice Age
The first sequencing of ancient genomes extracted from human remains that date back to the Late Upper Palaeolithic period over 13,000 years ago has revealed a previously unknown "fourth strand" of ancient European ancestry. This new lineage stems from populations of hunter-gatherers that split from western hunter-gatherers shortly after the 'out of Africa' expansion some 45,000 years ago and went on to settle in the Caucasus region, where southern Russia meets Georgia today. Here these...
https://www.biyologlar.com/fourth-strand-of-european-ancestry-originated-with-hunter-gatherers-isolated-by-ice-age -
New insights into a virus proteome
The genome encodes the complete information needed by an organism, including that required for protein production. Viruses, which are up to a thousand times smaller than human cells, have considerably smaller genomes. Using a type of herpesvirus as a model system, the scientists of the Max Planck Institute of Biochemistry in Martinsried near Munich and their collaboration partners at the University of California in San Francisco have shown that the genome of this virus contains much more...
https://www.biyologlar.com/new-insights-into-a-virus-proteome -
May repairs full of mistakes develop into cancer?
These are DNA double-strand breaks, introduced by ionizing radiation or other mechanisms, are repaired rapidly and precisely in normal cells (right pathway). In contrast, compromised Tel1 activation with inefficient end...
https://www.biyologlar.com/may-repairs-full-of-mistakes-develop-into-cancer -
May repairs full of mistakes develop into cancer?
These are DNA double-strand breaks, introduced by ionizing radiation or other mechanisms, are repaired rapidly and precisely in normal cells (right pathway). In contrast, compromised Tel1 activation with inefficient end...
https://www.biyologlar.com/may-repairs-full-of-mistakes-develop-into-cancer -
Bacterial DNA may integrate into human genome more readily in tumor tissue
Bacterial DNA may integrate into the human genome more readily in tumors than in normal human tissue, scientists have found. The researchers, affiliated with the University of Maryland School of Medicine's Institute for Genome Sciences, analyzed genomic sequencing data available from the Human Genome Project, the 1,000 Genomes Project and The Cancer Genome Atlas. They considered the phenomenon of lateral gene transfer (LGT), the transmission of genetic material between organisms in a manner...
https://www.biyologlar.com/bacterial-dna-may-integrate-into-human-genome-more-readily-in-tumor-tissue -
Watching 'jumping genes' in action
"Jumping genes" are ubiquitous. Every domain of life hosts these sequences of DNA that can "jump" from one position to another along a chromosome; in fact, nearly half the human genome is made up of jumping genes.
https://www.biyologlar.com/watching-jumping-genes-in-action -
Watching 'jumping genes' in action
"Jumping genes" are ubiquitous. Every domain of life hosts these sequences of DNA that can "jump" from one position to another along a chromosome; in fact, nearly half the human genome is made up of jumping genes.
https://www.biyologlar.com/watching-jumping-genes-in-action -
Genetic 'paint box' shuffled between butterfly species to create new wing patterns
New research on butterfly genomes has revealed that the genetic components that produce different splotches of colour on wings can be mixed up between species by interbreeding to create new patterns, like a "genetic paint-box". Research on Amazonian Heliconius butterflies has shown that two of the most common colour patterns, found in combination on the wings of many Heliconius species - the dennis red patch on the base of the forewing, and the ray red streaks that fan out across the hindwing...
https://www.biyologlar.com/genetic-paint-box-shuffled-between-butterfly-species-to-create-new-wing-patterns -
Common bacteria on verge of becoming antibiotic-resistant superbugs
Antibiotic resistance is poised to spread globally among bacteria frequently implicated in respiratory and urinary infections in hospital settings, according to new research at Washington University School of Medicine in St. Louis. The study shows that two genes that confer resistance against a particularly strong class of antibiotics can be shared easily among a family of bacteria responsible for a significant portion of hospital-associated infections. Drug-resistant germs in the same family...
https://www.biyologlar.com/common-bacteria-on-verge-of-becoming-antibiotic-resistant-superbugs -
The 'intraterrestrials': New viruses discovered in ocean depths
The intraterrestrials, they might be called. Strange creatures live in the deep sea, but few are odder than the viruses that inhabit deep ocean methane seeps and prey on single-celled microorganisms called archaea. The least understood of life's three primary domains, archaea thrive in the most extreme environments on the planet: near hot ocean rift vents, in acid mine drainage, in the saltiest of evaporation ponds and in petroleum deposits deep underground. Virus in the deep blue sea While...
https://www.biyologlar.com/the-intraterrestrials-new-viruses-discovered-in-ocean-depths -
DNA breaks in nerve cells' ancestors cluster in specific genes
The genome of developing brain cells harbors 27 clusters or hotspots where its DNA is much more likely to break in some places than others, researchers from the Program in Cellular and Molecular Medicine (PCMM) at Boston Children's Hospital, Harvard Medical School, and the Howard Hughes Medical Institute report in the journal Cell. Those hotspots appear in genes associated with brain tumors and a number of neurodevelopmental and neuropsychiatric conditions, raising new questions about these...
https://www.biyologlar.com/dna-breaks-in-nerve-cells-ancestors-cluster-in-specific-genes -
DNA breaks in nerve cells' ancestors cluster in specific genes
The genome of developing brain cells harbors 27 clusters or hotspots where its DNA is much more likely to break in some places than others, researchers from the Program in Cellular and Molecular Medicine (PCMM) at Boston Children's Hospital, Harvard Medical School, and the Howard Hughes Medical Institute report in the journal Cell. Those hotspots appear in genes associated with brain tumors and a number of neurodevelopmental and neuropsychiatric conditions, raising new questions about these...
https://www.biyologlar.com/dna-breaks-in-nerve-cells-ancestors-cluster-in-specific-genes -
Phages transducing antibiotic resistance detected in chicken meat
Bacteria resistant to antibiotics are on the rise. There are different explanations for how resistances are transferred. Researchers from the Vetmeduni Vienna found phages in chicken meat that are able to transfer antimicrobial resistance to bacteria. Phages are viruses that exclusively infect bacteria. They can contribute to the spread of antimicrobial resistance. The findings may also be relevant for clinical settings. The study was published in the journal Applied and Environmental...
https://www.biyologlar.com/phages-transducing-antibiotic-resistance-detected-in-chicken-meat -
Viruses revealed to be a major driver of human evolution
Aminopeptidase N is a protein that acts as a receptor for coronaviruses, the family of viruses behind recent epidemics of SARS and MERS, among others.
https://www.biyologlar.com/viruses-revealed-to-be-a-major-driver-of-human-evolution -
Viruses revealed to be a major driver of human evolution
Aminopeptidase N is a protein that acts as a receptor for coronaviruses, the family of viruses behind recent epidemics of SARS and MERS, among others.
https://www.biyologlar.com/viruses-revealed-to-be-a-major-driver-of-human-evolution -
NIH-funded study establishes genomic data set on Lassa virus
An international team of researchers has developed the largest genomic data set in the world on Lassa virus (LASV). The new genomic catalog contains nearly 200 viral genomes collected from patient samples in Sierra Leone and Nigeria, as well as field samples from the major animal reservoir, or host, of Lassa virus--the rodent Mastomys natalensis, also called the multimammate rat. The researchers show that LASV strains cluster into four major groups based on geographic location, with three in...
https://www.biyologlar.com/nih-funded-study-establishes-genomic-data-set-on-lassa-virus -
New fungi behind emerging wheat disease
Researchers have unraveled the mystery cause of the emerging wheat disease White Grain Disorder. Scientists at the Wheat Biosecurity Laboratory at The Australian National University (ANU) identified the cause of the disease when they isolated three previously undiscovered fungi from infected wheat samples and sequenced their genomes. "Until now, growers and pathologists have recognised the symptoms of White Grain Disorder, but they haven't known what causes it," said lead researcher Associate...
https://www.biyologlar.com/new-fungi-behind-emerging-wheat-disease -
Bacteria take 'RNA mug shots' of threatening viruses
Scientists from The University of Texas at Austin, the Stanford University School of Medicine and two other institutions have discovered that bacteria have a system that can recognize and disrupt dangerous
https://www.biyologlar.com/bacteria-take-rna-mug-shots-of-threatening-viruses -
Supercomputing the evolution of a model flower
Scientists using supercomputers found genes sensitive to cold and drought in a plant help it survive climate change. These findings increase basic understanding of plant adaptation and can be applied to improve crops.
https://www.biyologlar.com/supercomputing-the-evolution-of-a-model-flower -
Fruitful collaboration yields insight on the tomato genome
Plant biologist Julin Maloof met fellow researcher Neelima Sinha while beginning his career at the University of California, Davis. Both interested in plant morphology and natural variation,
https://www.biyologlar.com/fruitful-collaboration-yields-insight-on-the-tomato-genome -
Genetic road map may bring about better cotton crops
A University of Texas at Austin scientist, working with an international research team, has developed the most precise sequence map yet of U.S.
https://www.biyologlar.com/genetic-road-map-may-bring-about-better-cotton-crops -
DNA of bacteria crucial to ecosystem defies explanation
This image shows a colony of Trichodesmium.
https://www.biyologlar.com/dna-of-bacteria-crucial-to-ecosystem-defies-explanation -
Bumblebee genomes create a buzz in the field of pollination
Bees play a key role in our ecosystem and in the world's food supply.
https://www.biyologlar.com/bumblebee-genomes-create-a-buzz-in-the-field-of-pollination -
New clues found to how 'cruise-ship' virus gets inside cells
Researchers at Washington University School of Medicine in St. Louis have identified the protein that norovirus -- shown here in a colored transmission electron micrograph -- uses to invade cells
https://www.biyologlar.com/new-clues-found-to-how-cruise-ship-virus-gets-inside-cells -
New genus of bacteria found living inside hydraulic fracturing wells
Ohio State University researchers and their colleagues have identified a new genus of bacteria living inside hydraulic fracturing wells.
https://www.biyologlar.com/new-genus-of-bacteria-found-living-inside-hydraulic-fracturing-wells -
New genus of bacteria found living inside hydraulic fracturing wells
Ohio State University researchers and their colleagues have identified a new genus of bacteria living inside hydraulic fracturing wells.
https://www.biyologlar.com/new-genus-of-bacteria-found-living-inside-hydraulic-fracturing-wells -
Research shows that genomics can match plant variety to climate stresses
A new study on the genomic signatures of adaptation in crop plants can help predict how crop varieties respond to stress from their environments.
https://www.biyologlar.com/research-shows-that-genomics-can-match-plant-variety-to-climate-stresses -
Research shows that genomics can match plant variety to climate stresses
A new study on the genomic signatures of adaptation in crop plants can help predict how crop varieties respond to stress from their environments.
https://www.biyologlar.com/research-shows-that-genomics-can-match-plant-variety-to-climate-stresses -
Octopus genome reveals cephalopod secrets
Researchers from UC Berkeley, the Okinawa Institute of Science and Technology Graduate University and the University of Chicago have sequenced and annotated the first cephalopod genome
https://www.biyologlar.com/octopus-genome-reveals-cephalopod-secrets -
Scientists sequence first ancient Irish human genomes
Excavated near Belfast in 1855, she had lain in a Neolithic tomb chamber for 5,000 years; subsequently curated in Queens University Belfast.
https://www.biyologlar.com/scientists-sequence-first-ancient-irish-human-genomes -
Scientists sequence first ancient Irish human genomes
Excavated near Belfast in 1855, she had lain in a Neolithic tomb chamber for 5,000 years; subsequently curated in Queens University Belfast.
https://www.biyologlar.com/scientists-sequence-first-ancient-irish-human-genomes -
Sequencing of barley genome achieves new milestone
Barley is one of the world's most important cereal crops.
https://www.biyologlar.com/sequencing-of-barley-genome-achieves-new-milestone -
Sequencing of barley genome achieves new milestone
Barley is one of the world's most important cereal crops.
https://www.biyologlar.com/sequencing-of-barley-genome-achieves-new-milestone -
Duplicate DNA a hallmark of tick genome
Researchers sequence the genome of the Lyme-disease-causing tick and find lots of duplicative elements.
https://www.biyologlar.com/duplicate-dna-a-hallmark-of-tick-genome