Toplam 167 içerik listeleniyor
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Antibiotic resistance genes increasing
Antibiotic genes are increasing and are just a plane ride away. Around the world, antibiotic use and resistance is increasing while the discovery of new antibiotics has nearly halted.
https://www.biyologlar.com/antibiotic-resistance-genes-increasing-haber-8125 -
Primate evolution in the fast lane
The pace of evolution is typically measured in millions of years, as random, individual mutations accumulate over generations, but researchers at Cornell and Bar-Ilan Universities have uncovered a new mechanism for mutation in primates that is rapid, coordinated, and aggressive. The discovery raises questions about the accuracy of using the more typical mutation process as an estimate to date when two species diverged, as well as the extent to which this and related enzymes played a role in...
https://www.biyologlar.com/primate-evolution-in-the-fast-lane-haber-8133 -
Ant antennae provide vital ID information: Study
This image shows ants tending to some leave hoppers. University of Melbourne scientists have shone a new light into the complexities of ant communication, with the discovery that ants not only pick up information through their antennae, but also use them to convey social signals.
https://www.biyologlar.com/ant-antennae-provide-vital-id-information-study-haber-8717 -
Pancreas stem cell discovery may lead to new diabetes treatments
Stem cells in the adult pancreas have been identified that can be turned into insulin producing cells, a finding that means people with type 1 diabetes might one day be able to regenerate their own insulin-producing cells. The discovery was made by scientists from the Walter and Eliza Hall Institute and provides further evidence that stem cells don't only occur in the embryo. The ability to produce the hormone insulin is crucial for controlling blood sugar (glucose) levels. In people with...
https://www.biyologlar.com/pancreas-stem-cell-discovery-may-lead-to-new-diabetes-treatments -
New discovery in living cell signaling
A breakthrough discovery into how living cells process and respond to chemical information could help advance the development of treatments for a large number of cancers and other cellular disorders that have been resistant to therapy. An international collaboration of researchers, led by scientists with the U.S. Department of Energy (DOE)'s Lawrence Berkeley National Laboratory (Berkeley Lab) and the University of California (UC) Berkeley, have unlocked the secret behind the activation of the...
https://www.biyologlar.com/new-discovery-in-living-cell-signaling -
Simple technology makes CRISPR gene editing cheaper
University of California, Berkeley, researchers have discovered a much cheaper and easier way to target a hot new gene editing tool, CRISPR-Cas9, to cut or label DNA. The CRISPR-Cas9 technique, invented three years ago at UC Berkeley, has taken genomics by storm, with its ability to latch on to a very specific sequence of DNA and cut it, inactivating genes with ease. This has great promise for targeted gene therapy to cure genetic diseases, and for discovering the causes of disease. The...
https://www.biyologlar.com/simple-technology-makes-crispr-gene-editing-cheaper -
New method to grow zebrafish embryonic stem cells can regenerate whole fish
Zebrafish, a model organism that plays an important role in biological research and the discovery and development of new drugs and cell-based therapies, can form embryonic stem cells (ESCs).
https://www.biyologlar.com/new-method-to-grow-zebrafish-embryonic-stem-cells-can-regenerate-whole-fish -
Wisconsin scientists find genetic recipe to turn stem cells to blood
The ability to reliably and safely make in the laboratory all of the different types of cells in human blood is one key step closer to reality.
https://www.biyologlar.com/wisconsin-scientists-find-genetic-recipe-to-turn-stem-cells-to-blood -
Snake venom helps hydrogels stop the bleeding
A nanofiber hydrogel infused with snake venom may be the best material to stop bleeding quickly, according to Rice University scientists. The hydrogel called SB50 incorporates batroxobin, a venom produced by two species of South American pit viper. It can be injected as a liquid and quickly turns into a gel that conforms to the site of a wound, keeping it closed, and promotes clotting within seconds. Rice chemist Jeffrey Hartgerink, lead author Vivek Kumar and their colleagues reported their...
https://www.biyologlar.com/snake-venom-helps-hydrogels-stop-the-bleeding -
New brain mapping reveals unknown cell types
Using a process known as single cell sequencing, scientists at Karolinska Institutet have produced a detailed map of cortical cell types and the genes active within them. The study, which is published in the journal 'Science', marks the first time this method of analysis has been used on such a large scale on such complex tissue. The team studied over three thousand cells, one at a time, and even managed to identify a number of hitherto unknown types. "If you compare the brain to a fruit...
https://www.biyologlar.com/new-brain-mapping-reveals-unknown-cell-types -
Scientists create functional liver cells from stem cells
The liver plays a critical role in human metabolism. As the gatekeeper of the digestive track, this massive organ is responsible for drug breakdown and is therefore the first to be injured due to overdose or misuse. Evaluating this drug-induced liver injury is a critical part of pharmaceutical drug discovery and must be carried out on human liver cells. Regretfully, human liver cells, called hepatocytes, are in scarce supply as they can only be isolated from donated organs. Now, in research...
https://www.biyologlar.com/scientists-create-functional-liver-cells-from-stem-cells -
Restoring vision with stem cells
Age-related macular degeneration (AMRD) could be treated by transplanting photoreceptors produced by the directed differentiation of stem cells, thanks to findings published today by Professor Gilbert Bernier of the University of Montreal and its affiliated Maisonneuve-Rosemont Hospital. ARMD is a common eye problem caused by the loss of cones. Bernier's team has developed a highly effective in vitro technique for producing light sensitive retina cells from human embryonic stem cells. "Our...
https://www.biyologlar.com/restoring-vision-with-stem-cells -
Are embryonic stem cells and artificial stem cells equivalent?
Harvard Stem Cell Institute (HSCI) researchers at Massachusetts General Hospital and Harvard Medical School have found new evidence suggesting some human induced pluripotent stem cells are the 'functional equivalent' of human embryonic stem cells, a finding that may begin to settle a long running argument. The findings were published this week in Nature Biotechnology. From 1998 until 2007 embryonic stem cells (ES cells) were the only human cells known with the potential to become any other...
https://www.biyologlar.com/are-embryonic-stem-cells-and-artificial-stem-cells-equivalent -
Discovery of an unexpected function of a protein linked to neurodegenerative diseases
Until today, the proteins known as ubiquitin receptors have been associated mainly with protein degradation, a basic cell cleaning process. A new function now described for the protein dDsk2 by the team headed by Ferran Azorín, group leader at the Institute for Research in Biomedicine (IRB Barcelona) and CSIC research professor, links ubiquitin receptors for the first time with the regulation of gene expression. This discovery, published today in Nature Communications, opens up a double...
https://www.biyologlar.com/discovery-of-an-unexpected-function-of-a-protein-linked-to-neurodegenerative-diseases -
Discovery of an unexpected function of a protein linked to neurodegenerative diseases
Until today, the proteins known as ubiquitin receptors have been associated mainly with protein degradation, a basic cell cleaning process. A new function now described for the protein dDsk2 by the team headed by Ferran Azorín, group leader at the Institute for Research in Biomedicine (IRB Barcelona) and CSIC research professor, links ubiquitin receptors for the first time with the regulation of gene expression. This discovery, published today in Nature Communications, opens up a double...
https://www.biyologlar.com/discovery-of-an-unexpected-function-of-a-protein-linked-to-neurodegenerative-diseases -
Novel stem cell line avoids risk of introducing transplanted tumors
Human pluripotent stem cells (hPSC) can become any type of cell in the adult body, offering great potential in disease modeling, drug discovery and creating replacement cells for conditions ranging from cardiovascular to Alzheimer's disease. But that promise comes with a risk: the possibility that transplanted hPSCs might also develop as unwanted tumors. In a new study published November 10, 2015 in the online journal eLIFE, researchers at University of California, San Diego School of Medicine...
https://www.biyologlar.com/novel-stem-cell-line-avoids-risk-of-introducing-transplanted-tumors -
Discovery of an embryonic switch for cancer stem cell generation
An international team of scientists, headed by researchers at UC San Diego School of Medicine and UC San Diego Moores Cancer Center, report that decreases in a specific group of proteins trigger changes in the cancer microenvironment that accelerate growth and development of therapy-resistant cancer stem cells (CSCs). The discovery suggests the basis for a potential new therapeutic approach to eradicate blood cancers, which affect more than 1.1 million Americans. In fact, researchers found...
https://www.biyologlar.com/discovery-of-an-embryonic-switch-for-cancer-stem-cell-generation -
Odd histone helps suppress jumping genes in stem cells, study says
A family of proteins known as histones provides support and structure to DNA, but for years, scientists have been puzzling over occasional outliers among these histones, which appear to exist for specific, but often mysterious reasons. Now, researchers have uncovered a new purpose for one such histone variant: preventing genetic mutations by keeping certain so-called "jumping genes" in place. This research, which began at Rockefeller University and was published May 4 in Nature, reveals a...
https://www.biyologlar.com/odd-histone-helps-suppress-jumping-genes-in-stem-cells-study-says -
Decaying RNA molecules tell a story
Once messenger RNA (mRNA) has done its job - conveying the information to produce the proteins necessary for a cell to function - it is no longer required and is degraded. Scientists have long thought that the decay started after translation was complete and that decaying RNA molecules provided little biological information. Now a team from EMBL Heidelberg and Stanford University led by Lars Steinmetz has turned this on its head in an article published in Cell. The researchers have shown that...
https://www.biyologlar.com/decaying-rna-molecules-tell-a-story -
New way to harvest stem cells better for donors
Australian scientists have developed a new method for harvesting stem cells, which is less invasive and reduces side effects for donors.
https://www.biyologlar.com/new-way-to-harvest-stem-cells-better-for-donors -
A quartet of genes controls growth of blood stem cells
An important element in getting blood stem cells to multiply outside the body is to understand which of the approximately 20 000 genes in the human body control their growth. A research team at Lund University in Sweden has studied close to 15 000 of these genes alongside each other. The researchers have succeeded in identifying four key genes which, together, govern the growth and multiplication of the stem cells. The study is now being published in the journal Cell Reports. Every day, over...
https://www.biyologlar.com/a-quartet-of-genes-controls-growth-of-blood-stem-cells -
Small molecules change biological clock rhythm
A team of chemists and biologists at the Institute of Transformative Bio-Molecules (ITbM), Nagoya University have succeeded in finding new molecules that change the circadian rhythm in mammals by applying synthetic chemistry methods, which makes use of highly selective metal catalysts. Most living organisms have a biological clock with an approximately 24-hour circadian rhythm, which regulates important body functions such as sleep/wake cycles, hormone secretion, and metabolism. Disruption of...
https://www.biyologlar.com/small-molecules-change-biological-clock-rhythm -
Researchers use single molecule of DNA to create world's smallest diode
Researchers at the University of Georgia and at Ben-Gurion University in Israel have demonstrated for the first time that nanoscale electronic components can be made from single DNA molecules. Their study, published in the journal Nature Chemistry, represents a promising advance in the search for a replacement for the silicon chip. The finding may eventually lead to smaller, more powerful and more advanced electronic devices, according to the study's lead author, Bingqian Xu. "For 50 years,...
https://www.biyologlar.com/researchers-use-single-molecule-of-dna-to-create-worlds-smallest-diode -
Researchers use single molecule of DNA to create world's smallest diode
Researchers at the University of Georgia and at Ben-Gurion University in Israel have demonstrated for the first time that nanoscale electronic components can be made from single DNA molecules. Their study, published in the journal Nature Chemistry, represents a promising advance in the search for a replacement for the silicon chip. The finding may eventually lead to smaller, more powerful and more advanced electronic devices, according to the study's lead author, Bingqian Xu. "For 50 years,...
https://www.biyologlar.com/researchers-use-single-molecule-of-dna-to-create-worlds-smallest-diode -
Algae use their 'tails' to gallop and trot like quadrupeds
Long before there were fish swimming in the oceans, tiny microorganisms were using long slender appendages called cilia and flagella to navigate their watery habitats.
https://www.biyologlar.com/algae-use-their-tails-to-gallop-and-trot-like-quadrupeds -
These gigantic whales have nerves like bungee cords
Nerves aren't known for being stretchy. In fact, "nerve stretch injury" is a common form of trauma in humans. But researchers reporting in
https://www.biyologlar.com/these-gigantic-whales-have-nerves-like-bungee-cords -
Scientists discover oldest plant root stem cells
Scientists at Oxford University have discovered the oldest known population of plant root stem cells in a 320 million-year-old fossil.
https://www.biyologlar.com/scientists-discover-oldest-plant-root-stem-cells -
Mantis shrimp inspires next generation of ultra-strong materials
This is the herringbone structure of the outer layer (impact region) of the mantis shrimp dactyl club.
https://www.biyologlar.com/mantis-shrimp-inspires-next-generation-of-ultra-strong-materials -
Mantis shrimp inspires next generation of ultra-strong materials
This is the herringbone structure of the outer layer (impact region) of the mantis shrimp dactyl club.
https://www.biyologlar.com/mantis-shrimp-inspires-next-generation-of-ultra-strong-materials -
Breakthrough in scaling up life-changing stem cell production
Scientists have discovered a new method of creating human stem cells which could solve the big problem of the large-scale production needed to fully realise the potential of these remarkable cells for understanding and treating disease.
https://www.biyologlar.com/breakthrough-in-scaling-up-life-changing-stem-cell-production -
Four newly identified genes could improve rice
The GWAS results for genes that influence flowering dates. The known genes Hd1, Hd2, and Hd6 were located, together with two newly-identified genes that also affect flowering dates.
https://www.biyologlar.com/four-newly-identified-genes-could-improve-rice -
Four newly identified genes could improve rice
The GWAS results for genes that influence flowering dates. The known genes Hd1, Hd2, and Hd6 were located, together with two newly-identified genes that also affect flowering dates.
https://www.biyologlar.com/four-newly-identified-genes-could-improve-rice -
Gene fuels age-related obesity and diabetes
Practically everyone gets fatter as they get older, but some people can blame their genes for the extra padding. Researchers have shown that two different mutations in a gene called ankyrin-B cause cells to suck up glucose faster than normal, fattening them up and eventually triggering the type of diabetes linked to obesity. The more severe of the two mutations, called R1788W, is carried by nearly one million Americans. The milder mutation, known as L1622I, is shared by seven percent of the...
https://www.biyologlar.com/gene-fuels-age-related-obesity-and-diabetes -
Disease that causes blindness in children tied to new gene
Northwestern Medicine and University of Wisconsin-Madison (UW) scientists have identified a gene that causes severe glaucoma in children.
https://www.biyologlar.com/disease-that-causes-blindness-in-children-tied-to-new-gene -
Missing link found between brain, immune system -- with major disease implications
Vessels directly connecting brain, lymphatic system exist despite decades of doctrine that they don't Finding may have substantial implications for major neurological diseases Game-changing discovery opens new areas of research, transforms existing ones Major gap in understanding of the human body revealed 'They'll have to change the textbooks' CHARLOTTESVILLE, Va., June 1, 2015 - In a stunning discovery that overturns decades of textbook teaching, researchers at the University of...
https://www.biyologlar.com/missing-link-found-between-brain-immune-system-with-major-disease-implications -
Eukaryotes: A new timetable of evolution
Contaminated samples have evidently created some confusion in the timetable of life. On the basis of ultra-clean analyses, an international team, including scientists from the Max Planck Institute for Biogeochemistry, has disproved supposed evidence that eukaryotes originated 2.5 to 2.8 billion years ago. In contrast to prokaryotes such as bacteria, eukaryotes have a nucleus. Some researchers thought they had discovered molecular remnants of living organisms in rock samples up to 2.8 billion...
https://www.biyologlar.com/eukaryotes-a-new-timetable-of-evolution -
Deciphering the olfactory receptor code
In animals, numerous behaviors are governed by the olfactory perception of their surrounding world. Whether originating in the nose of a mammal or the antennas of an insect, perception results from the combined activation of multiple receptors located in these organs. Identifying the full repertoire of receptors stimulated by a given odorant would represent a key step in deciphering the code that mediates these behaviors. To this end, a tool that provides a complete olfactory receptor signature...
https://www.biyologlar.com/deciphering-the-olfactory-receptor-code -
'Golden jackals' of East Africa are actually 'golden wolves'
Despite their remarkably similar appearance, the "golden jackals" of East Africa and Eurasia are actually two entirely different species. The discovery, based on DNA evidence and reported in the Cell Press journal Current Biology on July 30, increases the overall biodiversity of the Canidae--the group including dogs, wolves, foxes, and jackals--from 35 living species to 36. "This represents the first discovery of a 'new' canid species in Africa in over 150 years," says Klaus-Peter Koepfli of...
https://www.biyologlar.com/golden-jackals-of-east-africa-are-actually-golden-wolves -
Scientists blueprint tiny cellular 'nanomachine'
Scientists have drawn up molecular blueprints of a tiny cellular 'nanomachine', whose evolution is an extraordinary feat of nature, by using one of the brightest X-ray sources on Earth. The scientists produced the structural map of this nanomachine - diacylglycerol kinase - by using a "hit and run" crystallography technique. In doing so, they have been able to understand how the tiny enzyme performs critical cellular duties - answering questions that have been on the table for over 50 years...
https://www.biyologlar.com/scientists-blueprint-tiny-cellular-nanomachine -
Discovery of a salamander in amber sheds light on evolution of Caribbean islands
More than 20 million years ago, a short struggle took place in what is now the Dominican Republic, resulting in one animal getting its leg bitten off by a predator just before it escaped. But in the confusion, it fell into a gooey resin deposit, to be fossilized and entombed forever in amber. The fossil record of that event has revealed something not known before - that salamanders once lived on an island in the Caribbean Sea. Today, they are nowhere to be found in the entire Caribbean...
https://www.biyologlar.com/discovery-of-a-salamander-in-amber-sheds-light-on-evolution-of-caribbean-islands -
Two proteins control the growth of the heart and its adaptation to high blood pressure
Researchers at the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC) have identified how two proteins control the growth of the heart and its adaptation to high blood pressure (hypertension). Lead investigator Dr. Guadalupe Sabio explains that the results, described in Nature Communications, not only increase our understanding of the mechanisms used by cardiac cells to grow and adapt, but could also help in the design of new strategies to treat heart failure caused by...
https://www.biyologlar.com/two-proteins-control-the-growth-of-the-heart-and-its-adaptation-to-high-blood-pressure -
Monsters Resurrected - Biggest Killer Dino
This is a better quality version to this video. Its all about Spinosaurus. I do not own this video or its content. All content belongs to Discovery Channel.
https://www.biyologlar.com/monsters-resurrected-biggest-killer-dino -
Large funnel-web spider find surprises scientists
Scientists studying funnel-web spiders at Booderee National Park near Jervis Bay on the New South Wales south coast have found a large example of an unexpected funnel-web species. The scientists believe the 50-millimetre spider is a species of the tree-dwelling genus Hadronyche, not the ground-dwelling genus Atrax, which includes the Sydney funnel-web, the only species reported in the Park's records. "It's remarkable that we have found this other species in Booderee National Park," said Dr...
https://www.biyologlar.com/large-funnel-web-spider-find-surprises-scientists -
Sonic hedgehog gene provides evidence that our limbs may have evolved from sharks' gills
Latest analysis shows that human limbs share a genetic programme with the gills of cartilaginous fishes such as sharks and skates, providing evidence to support a century-old theory on the origin of limbs that had been widely discounted.
https://www.biyologlar.com/sonic-hedgehog-gene-provides-evidence-that-our-limbs-may-have-evolved-from-sharks-gills -
Zooming in on bacterial weapons in 3-D
The plague, bacterial dysentery, and cholera have one thing in common: These dangerous diseases are caused by bacteria which infect their host using a sophisticated injection apparatus. Through needle-like structures, they release molecular agents into their host cell, thereby evading the immune response. Researchers at the Max Planck Institute for Biophysical Chemistry in Göttingen in cooperation with colleagues at the Max Planck Institute for Infection Biology in Berlin and the University of...
https://www.biyologlar.com/zooming-in-on-bacterial-weapons-in-3-d -
T cells use 'handshakes' to sort friends from foes
T cells, the security guards of the immune system, use a kind of mechanical "handshake" to test whether a cell they encounter is a friend or foe, a new study finds.
https://www.biyologlar.com/t-cells-use-handshakes-to-sort-friends-from-foes -
T cells use 'handshakes' to sort friends from foes
T cells, the security guards of the immune system, use a kind of mechanical "handshake" to test whether a cell they encounter is a friend or foe, a new study finds.
https://www.biyologlar.com/t-cells-use-handshakes-to-sort-friends-from-foes -
3-D motion of cold virus offers hope for improved drugs using Australia's fastest supercomputer
Melbourne researchers are now simulating in 3D, the motion of the complete human rhinovirus, the most frequent cause of the common cold, on Australia's fastest supercomputer, paving the way for new drug development. Rhinovirus infection is linked to about 70 per cent of all asthma exacerbations with more than 50 per cent of these patients requiring hospitalisation. Furthermore, over 35 per cent of patients with acute chronic obstructive pulmonary disease (COPD) are hospitalised each year due...
https://www.biyologlar.com/3-d-motion-of-cold-virus-offers-hope-for-improved-drugs-using-australias-fastest-supercomputer -
Akıllı Tasarım: Bilim mi Din mi?
Akıllı Tasarım (AT) hareketinin neyi savunduğunu, hangi iddialarda bulunduğuna geçmeden önce bu hareketin kökenleri, nasıl ve ne zaman ortaya çıktığıyla ilgili biraz bilgi vermek istiyorum. Akıllı Tasarım hareketi, merkezi ABD’de Washington eyaletinin Seattle şehrinde bulunan DI (Discovery Institute yani Keşif Enstitüsü)’nin CSC (Center for Science and Culture yani Bilim ve Kültür Merkezi) bölümünü tarafından ortaya koyulmuştur. DI, 1990 yılında...
https://www.biyologlar.com/akilli-tasarim-bilim-mi-din-mi -
Virus throws a wrench in the immune system
The cytomegalovirus (CMV) is a member of the herpesvirus family. Although most people carry CMV for life, it hardly ever makes them sick. Researchers from the Helmholtz Centre for Infection Research and from the USA have now unveiled long term consequences of the on-going presence of CMV: Later in life, more and more cells of the immune system concentrate on CMV, and as a result, the response against other viruses is weakened. These research results help to explain why the elderly are often...
https://www.biyologlar.com/virus-throws-a-wrench-in-the-immune-system