Toplam 87 içerik listeleniyor
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KÖK HÜCRELERE BAKIŞ:TANIMLAR, KAVRAMLAR ve SINIFLANDIRMALAR
İki binli yıllarla beraber kök hücrelerin rejeneratif tıp (yenileyici tıp) alanındaki öneminin giderek arttığını ve tıbbın geleceğini şekillendirme potansiyelini gözlemlemekteyiz.
https://www.biyologlar.com/kok-hucrelere-bakistanimlar-kavramlar-ve-siniflandirmalar -
Coral reefs in Palau surprisingly resistant to naturally acidified waters
Ocean researchers working on the coral reefs of Palau in 2011 and 2012 made two unexpected discoveries that could provide insight into corals' resistance and resilience to ocean acidification, and aid in the creation of a plan to protect them. The team collected water samples at nine points along a transect that stretched from the open ocean, across the barrier reef, into the lagoon and then into the bays and inlets around the Rock Islands of Palau, in the western Pacific Ocean. With each...
https://www.biyologlar.com/coral-reefs-in-palau-surprisingly-resistant-to-naturally-acidified-waters -
Improving the delivery of chemotherapy with graphene
A new study published in IOP Publishing's journal 2D Materials has proposed using graphene as an alternative coating for catheters to improve the delivery of chemotherapy drugs. The research suggests that placing graphene - an extremely thin sheet of carbon atoms - on the internal surfaces of intravenous catheters commonly used to deliver chemotherapy drugs into a patient's body will improve the efficacy of treatments, and reduce the potential of the catheters breaking. The study indicates...
https://www.biyologlar.com/improving-the-delivery-of-chemotherapy-with-graphene -
New discovery in living cell signaling
A breakthrough discovery into how living cells process and respond to chemical information could help advance the development of treatments for a large number of cancers and other cellular disorders that have been resistant to therapy. An international collaboration of researchers, led by scientists with the U.S. Department of Energy (DOE)'s Lawrence Berkeley National Laboratory (Berkeley Lab) and the University of California (UC) Berkeley, have unlocked the secret behind the activation of the...
https://www.biyologlar.com/new-discovery-in-living-cell-signaling -
Simple technology makes CRISPR gene editing cheaper
University of California, Berkeley, researchers have discovered a much cheaper and easier way to target a hot new gene editing tool, CRISPR-Cas9, to cut or label DNA. The CRISPR-Cas9 technique, invented three years ago at UC Berkeley, has taken genomics by storm, with its ability to latch on to a very specific sequence of DNA and cut it, inactivating genes with ease. This has great promise for targeted gene therapy to cure genetic diseases, and for discovering the causes of disease. The...
https://www.biyologlar.com/simple-technology-makes-crispr-gene-editing-cheaper -
Scientists discover an on-off switch for aging cells
Scientists at the Salk Institute have discovered an on-and-off "switch" in cells that may hold the key to healthy aging. This switch points to a way to encourage healthy cells to keep dividing and generating, for example, new lung or liver tissue, even in old age. In our bodies, newly divided cells constantly replenish lungs, skin, liver and other organs. However, most human cells cannot divide indefinitely–with each division, a cellular timekeeper at the ends of chromosomes shortens. When...
https://www.biyologlar.com/scientists-discover-an-on-off-switch-for-aging-cells -
Wisconsin scientists find genetic recipe to turn stem cells to blood
The ability to reliably and safely make in the laboratory all of the different types of cells in human blood is one key step closer to reality.
https://www.biyologlar.com/wisconsin-scientists-find-genetic-recipe-to-turn-stem-cells-to-blood -
Amniotic stem cells demonstrate healing potential
Rice University and Texas Children's Hospital scientists are using stem cells from amniotic fluid to promote the growth of robust, functional blood vessels in healing hydrogels.
https://www.biyologlar.com/amniotic-stem-cells-demonstrate-healing-potential -
New study shows parrotfish are critical to coral reef island building
As well as being a beautiful species capable of changing its colour, shape and even gender, new research published today shows that parrotfish, commonly found on healthy coral reefs, can also play a pivotal role in providing the sands necessary to build and maintain coral reef islands. The study, based on work in the Maldives and published in the journal Geology, found that parrotfish produced more than 85% of the new sand-grade sediment on the reefs around these reef islands. Reef islands...
https://www.biyologlar.com/new-study-shows-parrotfish-are-critical-to-coral-reef-island-building -
Scientists create functional liver cells from stem cells
The liver plays a critical role in human metabolism. As the gatekeeper of the digestive track, this massive organ is responsible for drug breakdown and is therefore the first to be injured due to overdose or misuse. Evaluating this drug-induced liver injury is a critical part of pharmaceutical drug discovery and must be carried out on human liver cells. Regretfully, human liver cells, called hepatocytes, are in scarce supply as they can only be isolated from donated organs. Now, in research...
https://www.biyologlar.com/scientists-create-functional-liver-cells-from-stem-cells -
How an RNA gene silences a whole chromosome
Researchers at Caltech have discovered how an abundant class of RNA genes, called long non-coding RNAs (lncRNAs, pronounced link RNAs) can regulate key genes. By studying an important lncRNA, called Xist, the scientists identified how this RNA gathers a group of proteins and ultimately prevents women from having an extra functional X-chromosome--a condition in female embryos that leads to death in early development. These findings mark the first time that researchers have uncovered the detailed...
https://www.biyologlar.com/how-an-rna-gene-silences-a-whole-chromosome -
Unpacking embryonic pluripotency
Researchers at EMBL's European Bioinformatics Institute (EMBL-EBI) and the Wellcome Trust- Medical Research Council Cambridge Stem Cell Institute at the University of Cambridge have identified factors that spark the formation of pluripotent cells.
https://www.biyologlar.com/unpacking-embryonic-pluripotency -
Forensic botany uses plant DNA to trace crimes
Sam Houston State University is advancing the field of forensic botany with the publication of two recent studies that use marijuana DNA to link drug supplies and pollen DNA to aid in forensic investigations. In an article published in the International Journal of Legal Medicine, faculty and students from the Department of Forensic Science report that they developed a test to individualize samples of marijuana that could be used to link drugs across cases. The study examined 11 cases...
https://www.biyologlar.com/forensic-botany-uses-plant-dna-to-trace-crimes -
Tough times for the tree of life on coral reefs
Marine scientists are calling for a re-think of how marine protected areas (MPAs) are planned and coordinated, following a global assessment of the conservation of tropical corals and fishes. Researchers from the Australian Research Council Centre of Excellence for Coral Reef Studies (Coral CoE), at James Cook University in Townsville, analysed the extent to which the evolutionary histories of corals and fishes are protected, rather than looking at individual species. "Our interest was in...
https://www.biyologlar.com/tough-times-for-the-tree-of-life-on-coral-reefs -
Small molecules change biological clock rhythm
A team of chemists and biologists at the Institute of Transformative Bio-Molecules (ITbM), Nagoya University have succeeded in finding new molecules that change the circadian rhythm in mammals by applying synthetic chemistry methods, which makes use of highly selective metal catalysts. Most living organisms have a biological clock with an approximately 24-hour circadian rhythm, which regulates important body functions such as sleep/wake cycles, hormone secretion, and metabolism. Disruption of...
https://www.biyologlar.com/small-molecules-change-biological-clock-rhythm -
Penn bioengineers show why lab-made stem cells might fail: Errors in DNA folding
Induced pluripotent stem cells hold promise for regenerative medicine because they can, in theory, turn into any type of tissue and because they are made from a patient's own adult cells, guaranteeing compatibility. However, the technique that turns adult cells into these iPS cells is not foolproof; after reverting to their pluripotent state, these cells don't always correctly differentiate back into adult cells. Researchers from the University of Pennsylvania have now discovered one of the...
https://www.biyologlar.com/penn-bioengineers-show-why-lab-made-stem-cells-might-fail-errors-in-dna-folding -
New procedure allows long-term culturing of adult stem cells
A new procedure developed at Massachusetts General Hospital (MGH) may revolutionize the culturing of adult stem cells. In their report that has been published online prior to its appearance in the August 6 issue of Cell Stem Cell, the team describes generating and expanding airway stem cells from the sorts of tissue samples collected during routine treatment of lung disorders. The overall approach appears applicable to several other tissue types, including skin and the linings of the...
https://www.biyologlar.com/new-procedure-allows-long-term-culturing-of-adult-stem-cells -
Tara Oceans expedition yields treasure trove of plankton data
In five related reports in this issue of the journal Science, a multinational team of researchers who spent three and a half years sampling the ocean's sunlit upper layers aboard the schooner Tara unveil the first officially reported global analyses of the Tara Oceans consortium. Planktonic life in the ocean is far more diverse than scientists knew, these reports show. They provide new resources for cataloguing the ocean's numerous planktonic organisms, which -- though critical to life on...
https://www.biyologlar.com/tara-oceans-expedition-yields-treasure-trove-of-plankton-data -
Thousands on one chip: New method to study proteins
Protein microarrays like this allow the investigation of thousands of proteins in a single experiment. Microarrays are only a few centimeters in size and host thousands of individual test spots...
https://www.biyologlar.com/thousands-on-one-chip-new-method-to-study-proteins -
Thousands on one chip: New method to study proteins
Protein microarrays like this allow the investigation of thousands of proteins in a single experiment. Microarrays are only a few centimeters in size and host thousands of individual test spots...
https://www.biyologlar.com/thousands-on-one-chip-new-method-to-study-proteins -
Missing link found between brain, immune system -- with major disease implications
Vessels directly connecting brain, lymphatic system exist despite decades of doctrine that they don't Finding may have substantial implications for major neurological diseases Game-changing discovery opens new areas of research, transforms existing ones Major gap in understanding of the human body revealed 'They'll have to change the textbooks' CHARLOTTESVILLE, Va., June 1, 2015 - In a stunning discovery that overturns decades of textbook teaching, researchers at the University of...
https://www.biyologlar.com/missing-link-found-between-brain-immune-system-with-major-disease-implications -
Scientists blueprint tiny cellular 'nanomachine'
Scientists have drawn up molecular blueprints of a tiny cellular 'nanomachine', whose evolution is an extraordinary feat of nature, by using one of the brightest X-ray sources on Earth. The scientists produced the structural map of this nanomachine - diacylglycerol kinase - by using a "hit and run" crystallography technique. In doing so, they have been able to understand how the tiny enzyme performs critical cellular duties - answering questions that have been on the table for over 50 years...
https://www.biyologlar.com/scientists-blueprint-tiny-cellular-nanomachine -
A new twist in genetic switches
Rice University researchers have a new twist for those clinging to old ideas about a basic biological process. The Rice lab of theoretical biological physicist Peter Wolynes reported this week that the activity of a master regulator in cells is determined by kinetics, a notion that counters decades-old classical models in molecular biology that attribute the control of genetic processes to the thermodynamics of biochemical reactions. The genetic switch in question relies on a recently...
https://www.biyologlar.com/a-new-twist-in-genetic-switches -
DNA research offers clues on cell mutation
A team of researchers from Colorado State University has been studying DNA damage in living cells to learn more about how genetic abnormalities arise. It has long been known that DNA molecules in every cell get constantly damaged by things from the outside environment, like sunlight, cigarette smoke and radiation. However, more recently researchers have discovered that sources from within the cell itself can sometimes be even more damaging. DNA, or deoxyribonucleic acid, is found in the...
https://www.biyologlar.com/dna-research-offers-clues-on-cell-mutation -
DNA research offers clues on cell mutation
A team of researchers from Colorado State University has been studying DNA damage in living cells to learn more about how genetic abnormalities arise. It has long been known that DNA molecules in every cell get constantly damaged by things from the outside environment, like sunlight, cigarette smoke and radiation. However, more recently researchers have discovered that sources from within the cell itself can sometimes be even more damaging. DNA, or deoxyribonucleic acid, is found in the...
https://www.biyologlar.com/dna-research-offers-clues-on-cell-mutation -
Scientists discover protein's starring role in genome stability, and possibly cancer prevention
If you have a soft spot for unsung heroes, you'll love a DNA repair protein called XPG. Scientists from the U.S. Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) discovered that XPG plays a previously unknown and critical role helping to maintain genome stability in human cells. Their findings also raise the possibility that the protein helps prevent breast, ovarian, and other cancers associated with defective BRCA genes. The research, which is published online Jan....
https://www.biyologlar.com/scientists-discover-proteins-starring-role-in-genome-stability-and-possibly-cancer-prevention -
Unlocking the secrets of gene expression
Your DNA governs more than just what color your eyes are and whether you can curl your tongue.
https://www.biyologlar.com/unlocking-the-secrets-of-gene-expression -
'Tree of life' for 2.3 million species released
A first draft of the "tree of life" for the roughly 2.3 million named species of animals, plants, fungi and microbes -- from platypuses to puffballs -- has been released. A collaborative effort among eleven institutions, the tree depicts the relationships among living things as they diverged from one another over time, tracing back to the beginning of life on Earth more than 3.5 billion years ago. Tens of thousands of smaller trees have been published over the years for select branches of the...
https://www.biyologlar.com/tree-of-life-for-2-3-million-species-released -
Are fish the greatest athletes on the planet?
When you think of the world's greatest athletes, names like Usain Bolt generally spring to mind, but scientists have discovered the best athletes could well be found in the water, covered in scales. Scientists have discovered that fish are far more effective at delivering oxygen throughout their body than almost any other animal, giving them the athletic edge over other species. "Fish exploit a mechanism that is up to 50-times more effective in releasing oxygen to their tissues than that...
https://www.biyologlar.com/are-fish-the-greatest-athletes-on-the-planet -
Sonic hedgehog gene provides evidence that our limbs may have evolved from sharks' gills
Latest analysis shows that human limbs share a genetic programme with the gills of cartilaginous fishes such as sharks and skates, providing evidence to support a century-old theory on the origin of limbs that had been widely discounted.
https://www.biyologlar.com/sonic-hedgehog-gene-provides-evidence-that-our-limbs-may-have-evolved-from-sharks-gills -
The great northern cod comeback
Once an icon of overfishing, mismanagement, and stock decline, the northern Atlantic cod is showing signs of recovery according to new research published today in the Canadian Journal of Fisheries and Aquatic Sciences. This research, led by Dr. George Rose, tracks what is arguably the most important comeback of any fish stock worldwide. Studying the great northern Atlantic cod stock complex off Newfoundland and Labrador, once considered among the largest cod stocks in the world before its...
https://www.biyologlar.com/the-great-northern-cod-comeback -
Scientists capture the elusive structure of essential digestive enzyme
Stylized graphic of SEC-SAXS data (with cyan cross-section showing the elution profile and magenta cross-section showing scattering profile) and the structure of the activated phenylalanine hydroxylase
https://www.biyologlar.com/scientists-capture-the-elusive-structure-of-essential-digestive-enzyme -
Scientists capture the elusive structure of essential digestive enzyme
Stylized graphic of SEC-SAXS data (with cyan cross-section showing the elution profile and magenta cross-section showing scattering profile) and the structure of the activated phenylalanine hydroxylase
https://www.biyologlar.com/scientists-capture-the-elusive-structure-of-essential-digestive-enzyme -
A key protein is discovered as essential for malaria parasite transmission to mosquitos
Two teams have independently discovered that a single regulatory protein acts as the master genetic switch that triggers the development of male and female sexual forms (termed gametocytes) of the malaria parasite, solving a long-standing mystery in parasite biology with important implications for human health. The protein, AP2-G, is necessary for activating a set of genes that initiate the development of gametocytes -- the only forms that are infectious to mosquitos. The research also gives...
https://www.biyologlar.com/a-key-protein-is-discovered-as-essential-for-malaria-parasite-transmission-to-mosquitos -
How mold on space station flowers is helping get us to Mars
When Scott Kelly tweeted a picture of moldy leaves on the current crop of zinnia flowers aboard the International Space Station, it could have looked like the science was doomed.
https://www.biyologlar.com/how-mold-on-space-station-flowers-is-helping-get-us-to-mars -
Scientists learn more about how star-shaped brain cells help us learn
A molecule that enables strong communication between our brain and muscles appears to also aid essential communication between our neurons, scientists report.
https://www.biyologlar.com/scientists-learn-more-about-how-star-shaped-brain-cells-help-us-learn -
Shape-shifting molecule tricks viruses into mutating themselves to death
A newly developed spectroscopy method is helping to clarify the poorly understood molecular process by which an anti-HIV drug induces lethal mutations in the virus's genetic material. The findings from the University of Chicago and the Massachusetts Institute of Technology could bolster efforts to develop the next generation of anti-viral treatments. Viruses can mutate rapidly in order to adapt to environmental pressure. This feature also helps them become resistant to anti-viral drugs. But...
https://www.biyologlar.com/shape-shifting-molecule-tricks-viruses-into-mutating-themselves-to-death -
A molecular alarm clock awakens resting ovules
Ovarian follicle of fruit fly, with chromosomes stained in green and dKDM5 protein stained in red.
https://www.biyologlar.com/a-molecular-alarm-clock-awakens-resting-ovules -
A molecular alarm clock awakens resting ovules
Ovarian follicle of fruit fly, with chromosomes stained in green and dKDM5 protein stained in red.
https://www.biyologlar.com/a-molecular-alarm-clock-awakens-resting-ovules -
The mysterious sexual life of the most primitive dragonfly
Hemiphlebia mirabilis is a rare species in every sense: it is the most primitive dragonfly known to man, it has unique reproductive behaviors and was believed to be extinct.
https://www.biyologlar.com/the-mysterious-sexual-life-of-the-most-primitive-dragonfly -
The mysterious sexual life of the most primitive dragonfly
Hemiphlebia mirabilis is a rare species in every sense: it is the most primitive dragonfly known to man, it has unique reproductive behaviors and was believed to be extinct.
https://www.biyologlar.com/the-mysterious-sexual-life-of-the-most-primitive-dragonfly -
Bacteria take 'RNA mug shots' of threatening viruses
Scientists from The University of Texas at Austin, the Stanford University School of Medicine and two other institutions have discovered that bacteria have a system that can recognize and disrupt dangerous
https://www.biyologlar.com/bacteria-take-rna-mug-shots-of-threatening-viruses -
Genetic road map may bring about better cotton crops
A University of Texas at Austin scientist, working with an international research team, has developed the most precise sequence map yet of U.S.
https://www.biyologlar.com/genetic-road-map-may-bring-about-better-cotton-crops -
Cracking the mystery of Zika virus replication
This is the structure of the ZIKV helicase in complex with RNA.
https://www.biyologlar.com/cracking-the-mystery-of-zika-virus-replication -
Cracking the mystery of Zika virus replication
This is the structure of the ZIKV helicase in complex with RNA.
https://www.biyologlar.com/cracking-the-mystery-of-zika-virus-replication -
Bumblebee genomes create a buzz in the field of pollination
Bees play a key role in our ecosystem and in the world's food supply.
https://www.biyologlar.com/bumblebee-genomes-create-a-buzz-in-the-field-of-pollination -
Octopus genome reveals cephalopod secrets
Researchers from UC Berkeley, the Okinawa Institute of Science and Technology Graduate University and the University of Chicago have sequenced and annotated the first cephalopod genome
https://www.biyologlar.com/octopus-genome-reveals-cephalopod-secrets -
Sequencing of barley genome achieves new milestone
Barley is one of the world's most important cereal crops.
https://www.biyologlar.com/sequencing-of-barley-genome-achieves-new-milestone -
Sequencing of barley genome achieves new milestone
Barley is one of the world's most important cereal crops.
https://www.biyologlar.com/sequencing-of-barley-genome-achieves-new-milestone -
Hot processor speeds up UK genome analysis
This is the world's first NGS bioinformatics processor Bio-IT Processor.
https://www.biyologlar.com/hot-processor-speeds-up-uk-genome-analysis