Toplam 143 içerik listeleniyor
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UW team stores digital images in DNA -- and retrieves them perfectly
Technology companies routinely build sprawling data centers to store all the baby pictures, financial transactions, funny cat videos and email messages its users hoard. But a new technique developed by University of Washington and Microsoft researchers could shrink the space needed to store digital data that today would fill a Walmart supercenter down to the size of a sugar cube. The team of computer scientists and electrical engineers has detailed one of the first complete systems to encode,...
https://www.biyologlar.com/uw-team-stores-digital-images-in-dna-and-retrieves-them-perfectly-haber-8723 -
Better global ocean management
Fishing boats at the harbor in Luderitz, Namibia. The small town is known for its crayfish industry. New groundbreaking research shows that with improved fishing approaches -- compared to business as usual -- the majority of the world's wild fisheries could be at healthy levels in just 10 years and global fish populations could double by 2050.
https://www.biyologlar.com/better-global-ocean-management-haber-8727 -
Gene therapy fully restores vision in mouse model of Leber congenital amaurosis
Mice lacking the protein retGC1, which is deficient in humans suffering Leber congenital amaurosis-1 (LCA1), a disorder that causes severe visual impairment beginning in infancy, received gene therapy to replace retGC1 and showed fully restored visual function that persisted for at least 6 months. The success of this approach strongly support clinical testing of a gene therapy targeted to the retinas of LCA1 patients, conclude the authors of the study published in Human Gene Therapy. The...
https://www.biyologlar.com/gene-therapy-fully-restores-vision-in-mouse-model-of-leber-congenital-amaurosis-haber-8761 -
Study documents catastrophic collapse of Sahara's wildlife
A new study led by the Wildlife Conservation Society and Zoological Society or London warns that the world's largest tropical desert, the Sahara, has suffered a catastrophic collapse of its wildlife populations. The study by more than 40 authors representing 28 scientific organizations assessed 14 desert species and found that a shocking half of those are regionally extinct or confined to one percent or less of their historical range. A chronic lack of studies across the region due to past and...
https://www.biyologlar.com/study-documents-catastrophic-collapse-of-saharas-wildlife -
Stem cells + nanofibers = Promising nerve research
Every week in his clinic at the University of Michigan, neurologist Joseph Corey, M.D., Ph.D., treats patients whose nerves are dying or shrinking due to disease or injury.
https://www.biyologlar.com/stem-cells-nanofibers-promising-nerve-research -
Magnetic nanoparticles could be key to effective immunotherapy
In recent years, researchers have hotly pursued immunotherapy, a promising form of treatment that relies on harnessing and training the body's own immune system to better fight cancer and infection. Now, results of a study led by Johns Hopkins investigators suggests that a device composed of a magnetic column paired with custom-made magnetic nanoparticles may hold a key to bringing immunotherapy into widespread and successful clinical use. A summary of the research, conducted in mouse and human...
https://www.biyologlar.com/magnetic-nanoparticles-could-be-key-to-effective-immunotherapy -
Stem-cell approach shows promise for Duchenne muscular dystrophy
Researchers have shown that transplanting stem cells derived from normal mouse blood vessels into the hearts of mice that model the pathology associated with Duchenne muscular dystrophy (DMD) prevents the decrease in heart function associated with DMD. Their findings appear in the journal Stem Cells Translational Medicine. Duchenne muscular dystrophy is a genetic disorder caused by a mutation in the gene for dystrophin, a protein that anchors muscle cells in place when they contract. Without...
https://www.biyologlar.com/stem-cell-approach-shows-promise-for-duchenne-muscular-dystrophy -
New resource makes gene-editing technology even more user friendly
Researchers at Harvard University and the University of California, San Diego, have developed a new user-friendly resource to accompany the powerful gene editing tool called CRISPR/Cas9, which has been widely adopted to make precise, targeted changes in DNA. This breakthrough has the potential to facilitate new discoveries in gene therapies and basic genetics research. The research was published in the July 13 issue of Nature Methods. The study describes an approach to simplify a laborious...
https://www.biyologlar.com/new-resource-makes-gene-editing-technology-even-more-user-friendly -
Simple technology makes CRISPR gene editing cheaper
University of California, Berkeley, researchers have discovered a much cheaper and easier way to target a hot new gene editing tool, CRISPR-Cas9, to cut or label DNA. The CRISPR-Cas9 technique, invented three years ago at UC Berkeley, has taken genomics by storm, with its ability to latch on to a very specific sequence of DNA and cut it, inactivating genes with ease. This has great promise for targeted gene therapy to cure genetic diseases, and for discovering the causes of disease. The...
https://www.biyologlar.com/simple-technology-makes-crispr-gene-editing-cheaper -
Stem cell breakthrough could set up future transplant therapies
A new method for creating stem cells for the human liver and pancreas, which could enable both cell types to be grown in sufficient quantities for clinical use, has been developed by scientists. Using the technique, researchers have for the first time been able to grow a pure, self-renewing population of stem cells specific to the human foregut, the upper section of the human digestive system. These so-called "Foregut stem cells" could then be developed further to produce liver or pancreatic...
https://www.biyologlar.com/stem-cell-breakthrough-could-set-up-future-transplant-therapies -
Firefly protein enables visualization of roots in soil
Plants form a vast network of below-ground roots that search soil for needed resources. The structure and function of this root network can be highly adapted to particular environments such as desert soils where plants like Mesquite develop tap roots capable of digging 50 meters deep to capture precious water resources. Excavation of root systems reveals these kinds of adaptations but is laborious, time consuming, and does not provide information on how growing roots behave. A new imaging tool...
https://www.biyologlar.com/firefly-protein-enables-visualization-of-roots-in-soil -
Using DNA origami to build nanodevices of the future
Scientists have been studying ways to use synthetic DNA as a building block for smaller and faster devices. DNA has the advantage of being inherently "coded". Each DNA strand is formed of one of four "codes" that can link to only one complementary code each, thus binding two DNA strands together. Scientists are using this inherent coding to manipulate and "fold" DNA to form "origami nanostructures": extremely small two- and three-dimensional shapes that can then be used as construction material...
https://www.biyologlar.com/using-dna-origami-to-build-nanodevices-of-the-future -
Using DNA origami to build nanodevices of the future
Scientists have been studying ways to use synthetic DNA as a building block for smaller and faster devices. DNA has the advantage of being inherently "coded". Each DNA strand is formed of one of four "codes" that can link to only one complementary code each, thus binding two DNA strands together. Scientists are using this inherent coding to manipulate and "fold" DNA to form "origami nanostructures": extremely small two- and three-dimensional shapes that can then be used as construction material...
https://www.biyologlar.com/using-dna-origami-to-build-nanodevices-of-the-future -
ARITMA TESİSLERİ VE PROTOZOA
Çalışma metodları birbirinden farklı olsa da arıtma tesislerinin tamamı çeşitli protozoon gruplarını barındırır (Çizelge 1). Biyolojik unsurlar organik madde üzerinden beslenerek organik maddenin topaklaşmasını ve çökmesini sağlarlar. Bakteri bu maddelerin sıvı fazdan uzaklaştırılmasında rol alan en etkin organizma grubunu oluştur. Protozoonlar, atık su arıtma sistemlerinde biyolojik parçalanmadan sorumlu bakteriler üzerinden beslendiklerinden dolayı, önceleri...
https://www.biyologlar.com/aritma-tesisleri-ve-protozoa -
Chip-based technology enables reliable direct detection of Ebola virus
A team led by researchers at UC Santa Cruz has developed chip-based technology for reliable detection of Ebola virus and other viral pathogens. The system uses direct optical detection of viral molecules and can be integrated into a simple, portable instrument for use in field situations where rapid, accurate detection of Ebola infections is needed to control outbreaks. Laboratory tests using preparations of Ebola virus and other hemorrhagic fever viruses showed that the system has the...
https://www.biyologlar.com/chip-based-technology-enables-reliable-direct-detection-of-ebola-virus -
New method to grow zebrafish embryonic stem cells can regenerate whole fish
Zebrafish, a model organism that plays an important role in biological research and the discovery and development of new drugs and cell-based therapies, can form embryonic stem cells (ESCs).
https://www.biyologlar.com/new-method-to-grow-zebrafish-embryonic-stem-cells-can-regenerate-whole-fish -
Detecting HIV diagnostic antibodies with DNA nanomachines
New research may revolutionize the slow, cumbersome and expensive process of detecting the antibodies that can help with the diagnosis of infectious and auto-immune diseases such as rheumatoid arthritis and HIV. An international team of researchers have designed and synthetized a nanometer-scale DNA "machine" whose customized modifications enable it to recognize a specific target antibody. Their new approach, which they described this month in Angewandte Chemie, promises to support the...
https://www.biyologlar.com/detecting-hiv-diagnostic-antibodies-with-dna-nanomachines -
Wisconsin scientists find genetic recipe to turn stem cells to blood
The ability to reliably and safely make in the laboratory all of the different types of cells in human blood is one key step closer to reality.
https://www.biyologlar.com/wisconsin-scientists-find-genetic-recipe-to-turn-stem-cells-to-blood -
Virginia Tech researchers take cue from spider glue in efforts to create new materials
A taut tug on the line signals the arrival of dinner, and the leggy spider dashes across the web to find a tasty squirming insect. The spider, known as an orb weaver, must perfectly execute this moment, from a lightning-fast reaction to an artfully spun web glistening with sticky glue. This glue -- created when glycoproteins are secreted from a spider's abdomen and interact with the atmosphere -- has been studied for the past 12 years by Brent Opell, a professor of biological sciences in the...
https://www.biyologlar.com/virginia-tech-researchers-take-cue-from-spider-glue-in-efforts-to-create-new-materials -
EMBO Conference Series Chemical Biology 2012
Latest News•Registration is open! •Event poster is now available for download Why You Should Attend•SummaryChemical Biology is a quickly growing highly interdisciplinary field, which investigates biological questions by using chemical strategies and tools. It has emerged to become an important and central discipline by itself complementing areas such as medicinal chemistry, pharmacology, cell biology, structural biology and biochemistry. Researchers in Chemical Biology find...
https://www.biyologlar.com/embo-conference-series-chemical-biology-2012 -
Functional human liver cells grown in the lab
In new research appearing in the prestigious journal Nature Biotechnology, an international research team led by The Hebrew University of Jerusalem describes a new technique for growing human hepatocytes in the laboratory. This groundbreaking development could help advance a variety of liver-related research and applications, from studying drug toxicity to creating bio-artificial liver support for patients awaiting transplantations. The liver is the largest internal organ in the human body,...
https://www.biyologlar.com/functional-human-liver-cells-grown-in-the-lab -
Jeofiziksel değil, çevresel bir bariyer: Anadolu Diyagonali
Şekil 1. Anadolu ve yakın çevresinde biyolojik çeşitlilik sıcak noktaları.
https://www.biyologlar.com/jeofiziksel-degil-cevresel-bir-bariyer-anadolu-diyagonali -
Broad, MIT scientists overcome key CRISPR-Cas9 genome editing hurdle
Researchers at the Broad Institute of MIT and Harvard and the McGovern Institute for Brain Research at MIT have engineered changes to the revolutionary CRISPR-Cas9 genome editing system that significantly cut down on "off-target" editing errors. The refined technique addresses one of the major technical issues in the use of genome editing. The CRISPR-Cas9 system works by making a precisely targeted modification in a cell's DNA. The protein Cas9 alters the DNA at a location that is specified by...
https://www.biyologlar.com/broad-mit-scientists-overcome-key-crispr-cas9-genome-editing-hurdle -
Restoring vision with stem cells
Age-related macular degeneration (AMRD) could be treated by transplanting photoreceptors produced by the directed differentiation of stem cells, thanks to findings published today by Professor Gilbert Bernier of the University of Montreal and its affiliated Maisonneuve-Rosemont Hospital. ARMD is a common eye problem caused by the loss of cones. Bernier's team has developed a highly effective in vitro technique for producing light sensitive retina cells from human embryonic stem cells. "Our...
https://www.biyologlar.com/restoring-vision-with-stem-cells -
Great Barrier Reef marine reserves combat coral disease
A new and significant role for marine reserves on the Great Barrier Reef has been revealed, with researchers finding the reserves reduce the prevalence of coral diseases. It's been known for some time that marine reserves are important for maintaining and enhancing fish stocks, but this is the first time marine reserves have been shown to enhance coral health on the Great Barrier Reef. Researchers from the ARC Centre of Excellence for Coral Reef Studies at James Cook University found that...
https://www.biyologlar.com/great-barrier-reef-marine-reserves-combat-coral-disease -
Shiny fish skin inspires nanoscale light reflectors
A nature-inspired method to model the reflection of light from the skin of silvery fish and other organisms may be possible, according to Penn State researchers. Such a technique may be applicable to developing better broadband reflectors and custom multi-spectral filters for a wide variety of applications, including advanced optical coatings for glass, laser protection, infrared imaging systems, optical communication systems and photovoltaics, according to Douglas Werner, John L. and...
https://www.biyologlar.com/shiny-fish-skin-inspires-nanoscale-light-reflectors -
Novel stem cell line avoids risk of introducing transplanted tumors
Human pluripotent stem cells (hPSC) can become any type of cell in the adult body, offering great potential in disease modeling, drug discovery and creating replacement cells for conditions ranging from cardiovascular to Alzheimer's disease. But that promise comes with a risk: the possibility that transplanted hPSCs might also develop as unwanted tumors. In a new study published November 10, 2015 in the online journal eLIFE, researchers at University of California, San Diego School of Medicine...
https://www.biyologlar.com/novel-stem-cell-line-avoids-risk-of-introducing-transplanted-tumors -
Proteomics identifies DNA repair toolbox
During each cell division, more than 3.3 billion base pairs of genomic DNA have to be duplicated and segregated accurately to daughter cells. But what happens when the DNA template is damaged in such a way that the replication machinery gets stuck?
https://www.biyologlar.com/proteomics-identifies-dna-repair-toolbox -
Discovery of an embryonic switch for cancer stem cell generation
An international team of scientists, headed by researchers at UC San Diego School of Medicine and UC San Diego Moores Cancer Center, report that decreases in a specific group of proteins trigger changes in the cancer microenvironment that accelerate growth and development of therapy-resistant cancer stem cells (CSCs). The discovery suggests the basis for a potential new therapeutic approach to eradicate blood cancers, which affect more than 1.1 million Americans. In fact, researchers found...
https://www.biyologlar.com/discovery-of-an-embryonic-switch-for-cancer-stem-cell-generation -
Odd histone helps suppress jumping genes in stem cells, study says
A family of proteins known as histones provides support and structure to DNA, but for years, scientists have been puzzling over occasional outliers among these histones, which appear to exist for specific, but often mysterious reasons. Now, researchers have uncovered a new purpose for one such histone variant: preventing genetic mutations by keeping certain so-called "jumping genes" in place. This research, which began at Rockefeller University and was published May 4 in Nature, reveals a...
https://www.biyologlar.com/odd-histone-helps-suppress-jumping-genes-in-stem-cells-study-says -
Decaying RNA molecules tell a story
Once messenger RNA (mRNA) has done its job - conveying the information to produce the proteins necessary for a cell to function - it is no longer required and is degraded. Scientists have long thought that the decay started after translation was complete and that decaying RNA molecules provided little biological information. Now a team from EMBL Heidelberg and Stanford University led by Lars Steinmetz has turned this on its head in an article published in Cell. The researchers have shown that...
https://www.biyologlar.com/decaying-rna-molecules-tell-a-story -
Griffith uses 3-D tissue engineering to revolutionize dental disease
The discomfort and stigma of loose or missing teeth could be a thing of the past as Griffith University researchers pioneer the use of 3D bioprinting to replace missing teeth and bone. The three-year study, which has been granted a National Health and Medical Research Council Grant of $650,000, is being undertaken by periodontist Professor Saso Ivanovski from Griffith's Menzies Health Institute Queensland. As part of an Australian first, Professor Ivanovski and his team are using the latest...
https://www.biyologlar.com/griffith-uses-3-d-tissue-engineering-to-revolutionize-dental-disease -
Small molecules change biological clock rhythm
A team of chemists and biologists at the Institute of Transformative Bio-Molecules (ITbM), Nagoya University have succeeded in finding new molecules that change the circadian rhythm in mammals by applying synthetic chemistry methods, which makes use of highly selective metal catalysts. Most living organisms have a biological clock with an approximately 24-hour circadian rhythm, which regulates important body functions such as sleep/wake cycles, hormone secretion, and metabolism. Disruption of...
https://www.biyologlar.com/small-molecules-change-biological-clock-rhythm -
Stem cell therapy improves outcomes in severe heart failure
A new stem cell therapy significantly improved long-term health outcomes in patients with severe and end-stage heart failure in a study presented at the American College of Cardiology's 65th Annual Scientific Session.
https://www.biyologlar.com/stem-cell-therapy-improves-outcomes-in-severe-heart-failure -
Penn bioengineers show why lab-made stem cells might fail: Errors in DNA folding
Induced pluripotent stem cells hold promise for regenerative medicine because they can, in theory, turn into any type of tissue and because they are made from a patient's own adult cells, guaranteeing compatibility. However, the technique that turns adult cells into these iPS cells is not foolproof; after reverting to their pluripotent state, these cells don't always correctly differentiate back into adult cells. Researchers from the University of Pennsylvania have now discovered one of the...
https://www.biyologlar.com/penn-bioengineers-show-why-lab-made-stem-cells-might-fail-errors-in-dna-folding -
Stem cell transplant from young to old can heal stomach ulcers
Bethesda, MD (June 16, 2016) -- Basic and translational research paves the way for breakthroughs that can ultimately change patient care. Three new studies from Cellular and Molecular Gastroenterology and Hepatology (CMGH) -- AGA's basic and translational open-access journal -- provide a glimpse into future treatment strategies for stomach ulcers, inflammatory bowel disease and alcoholic liver disease. Please find summaries below. To speak with the journal authors, please email...
https://www.biyologlar.com/stem-cell-transplant-from-young-to-old-can-heal-stomach-ulcers -
New procedure allows long-term culturing of adult stem cells
A new procedure developed at Massachusetts General Hospital (MGH) may revolutionize the culturing of adult stem cells. In their report that has been published online prior to its appearance in the August 6 issue of Cell Stem Cell, the team describes generating and expanding airway stem cells from the sorts of tissue samples collected during routine treatment of lung disorders. The overall approach appears applicable to several other tissue types, including skin and the linings of the...
https://www.biyologlar.com/new-procedure-allows-long-term-culturing-of-adult-stem-cells -
Gene Drive Technology: Where is the future?
Gene drive technologies may one day help alleviate the burden caused by diseases transmitted by mosquitoes and other animal vectors.
https://www.biyologlar.com/gene-drive-technology-where-is-the-future -
Gene Drive Technology: Where is the future?
Gene drive technologies may one day help alleviate the burden caused by diseases transmitted by mosquitoes and other animal vectors.
https://www.biyologlar.com/gene-drive-technology-where-is-the-future -
Türkiye Zootekni Bölümlerinde Hayvan Davranışları Bilimi
Hayvan davranışları bilimi bakımından Türkiye’de son yıllarda sevindirici gelişmeler yaşanmaktadır. Lisans ve lisansüstü ders olarak hayvan davranışları, zootekni bölümü olan neredeyse tüm üniversitelerde okutulmaya başlanmıştır. Genellikle lisansta zorunlu ders olarak genel hayvan davranışları verilmekte, lisansüstünde ise seçmeli ders olarak türlere özgü davranış dersleri yer almaktadır. Ülkemizde davranış derslerinin türlere özgünleşmesi...
https://www.biyologlar.com/turkiye-zootekni-bolumlerinde-hayvan-davranislari-bilimi -
Thousands on one chip: New method to study proteins
Protein microarrays like this allow the investigation of thousands of proteins in a single experiment. Microarrays are only a few centimeters in size and host thousands of individual test spots...
https://www.biyologlar.com/thousands-on-one-chip-new-method-to-study-proteins -
Thousands on one chip: New method to study proteins
Protein microarrays like this allow the investigation of thousands of proteins in a single experiment. Microarrays are only a few centimeters in size and host thousands of individual test spots...
https://www.biyologlar.com/thousands-on-one-chip-new-method-to-study-proteins -
CRISPR gene editing reveals new therapeutic approach for blood disorders
This is a scanning electron micrograph of sickled and other red blood cells.
https://www.biyologlar.com/crispr-gene-editing-reveals-new-therapeutic-approach-for-blood-disorders -
CRISPR gene editing reveals new therapeutic approach for blood disorders
This is a scanning electron micrograph of sickled and other red blood cells.
https://www.biyologlar.com/crispr-gene-editing-reveals-new-therapeutic-approach-for-blood-disorders -
How a single molecule turns one immune cell into another
All it takes is one molecule to reprogram an antibody-producing B cell into a scavenging macrophage. This transformation is possible, new evidence shows, because the molecule (C/EBPa, a transcription factor) "short-circuits" the cells so that they re-express genes reserved for embryonic development. The findings appear July 30 in Stem Cell Reports, the journal of the International Society for Stem Cell Research. Over the past 28 years, researchers have shown that a number of specialized cell...
https://www.biyologlar.com/how-a-single-molecule-turns-one-immune-cell-into-another -
Missing link found between brain, immune system -- with major disease implications
Vessels directly connecting brain, lymphatic system exist despite decades of doctrine that they don't Finding may have substantial implications for major neurological diseases Game-changing discovery opens new areas of research, transforms existing ones Major gap in understanding of the human body revealed 'They'll have to change the textbooks' CHARLOTTESVILLE, Va., June 1, 2015 - In a stunning discovery that overturns decades of textbook teaching, researchers at the University of...
https://www.biyologlar.com/missing-link-found-between-brain-immune-system-with-major-disease-implications -
Many endangered species are back -- but face new struggles
A study of marine mammals and other protected species finds that several once endangered species, including the iconic humpback whale, the northern elephant seal and green sea turtles, have recovered and are repopulating their former ranges. The research, published in the June edition of Trends in Ecology and Evolution, suggests that some species, including humpback whales, have reached population levels that may warrant removal from endangered species lists. But returning species, which defy...
https://www.biyologlar.com/many-endangered-species-are-back-but-face-new-struggles -
Purest yet liver-like cells generated from induced pluripotent stem cells
This image shows induced pluripotent stem cells expressing a characteristic cell surface protein called SSEA4 (green).
https://www.biyologlar.com/purest-yet-liver-like-cells-generated-from-induced-pluripotent-stem-cells -
Purest yet liver-like cells generated from induced pluripotent stem cells
This image shows induced pluripotent stem cells expressing a characteristic cell surface protein called SSEA4 (green).
https://www.biyologlar.com/purest-yet-liver-like-cells-generated-from-induced-pluripotent-stem-cells -
Eukaryotes: A new timetable of evolution
Contaminated samples have evidently created some confusion in the timetable of life. On the basis of ultra-clean analyses, an international team, including scientists from the Max Planck Institute for Biogeochemistry, has disproved supposed evidence that eukaryotes originated 2.5 to 2.8 billion years ago. In contrast to prokaryotes such as bacteria, eukaryotes have a nucleus. Some researchers thought they had discovered molecular remnants of living organisms in rock samples up to 2.8 billion...
https://www.biyologlar.com/eukaryotes-a-new-timetable-of-evolution